The most common question you may have seen lately regarding MK-677 is how long it takes for MK-677 to leave your system. Well, you will find different answers to this question. However, the most authentic answer to this question is provided here:
“MK-677 has a long half-life, and it may take anywhere from 4 weeks to 6 months to completely leave your system.“
Let’s dive deeper into this topic to understand it in more detail.
What is the Half-Life of MK-677?
MK-677 has a longer half-life than many other compounds. The half-life of the compound is estimated to be around 24 hours. This means that it takes approximately 24 hours for half of the MK-677 to be eliminated from your system.
How Long is MK-677 Detected in the System?
It is believed that MK-677 may remain detectable in the human body for up to 14 days or even several weeks after the last dose. Due to its long half-life, however, MK-677 could potentially stay detectable for months.
Various studies claim that MK-677 is detectable in the body for up to several months. There is one study that has shown that:
“MK-677 remains in the hair sample of equine for up to 209 days and 358 days in tail hair”. [1]
How Long is MK-677 Detectable in Blood?
It is said that MK-677 can be detectable in the blood sample of humans for 12 to 24 hours since the last dose.
How Long Can MK-677 Be Detected in Urine?
MK-677 remains detectable in the urine for up to 90 days since your last dose. Unlike many other substances, MK-677 is not rapidly eliminated by the kidneys and liver.
What Factors Influence MK-677’s Detection Time?
Though MK-677 stays in your system for a longer time, a few factors may intervene such as:
- Dosage
- Metabolism
- Cycle Length
Dosage:
How much time MK-677 stays in your system depends on how much you are taking. Some people take a single dose a day, while others prefer to split the dose. A single 20 mg dose of MK-677 may exert its effects for up to 3 months.
“A research on elderly subjects has described that MK-677 serum IGF-1 levels remain in the system for at least for 4 weeks”. [1]
Metabolism:
The metabolism of the person also plays a crucial role in determining how long MK-677 stays in the system.
- Fast Metabolism and Lower Dose
If a person has a fast metabolism and takes a lower dose there is a chance that MK-677 will be eliminated quickly from their body. In this case, the MK-677 effects will stay in the system for up to 4 – 7 weeks.
- Slow Metabolism and Higher Dose
If a person has a slower metabolism and takes higher doses the effects may last in the system for up to several months. That is because slow metabolism takes a long time to eliminate the MK-677 drug’s effects from the system.
Cycle Length:
If someone uses MK-677 for an extended time or has been using it for several months, the detection time will surely increase. It stays in the body for longer and does not leave the system soon.
What Does MK-677 do?
MK-677 also known by the name Ibutamoren is a nonpeptide that targets the ghrelin receptor. Ghrelin is a brain receptor that plays an important role in stimulating appetite and growth hormone (GH) release. [2]
By targeting and activating the ghrelin receptors, MK-677 may boost the production of growth hormone(GH). Increased GH levels improve muscle growth, boost metabolism, enhance bone density, and improve overall cellular repair. [1]
Can MK-677 Make You Taller?
Yes, It is believed that higher GH levels may increase your height. However, this is only true if your growth plates have not yet closed. Using MK-677 after your growth plates have fused will offer no benefit to your height.
Will MK-677 be Detected in a Drug Test?
Yes, MK-677 can be detected in a drug test, particularly in athletic or anti-doping testing. The compound remains in the body for several weeks and months. Therefore, any athlete should avoid using it.
References
- Murphy, M. G., Plunkett, L. M., Gertz, B. J., He, W., Wittreich, J., Polvino, W. M., & Clemmons, D. R. (1998). MK-677, an orally active growth hormone secretagogue, reverses diet-induced catabolism. The Journal of Clinical Endocrinology and Metabolism, 83(2), 320–325. https://doi.org/10.1210/jcem.83.2.4551
