Talk about safe and effective nootropics and people think of the obvious ones: Piracetam and Modafinil or, more recently, Mind Lab Pro and Performance Lab Mind. Fair enough, all these smart drugs have proven themselves in multiple studies.
But as more people use these brain supplements, their side effects become increasingly prominent. This gives other nootropics the chance to make their mark. Especially those that have already proven their efficacy in clinical trials. And whom researchers back for being safe.
Centrophenoxine is one such nootropic. It has demonstrated its ability to improve memory and focus in multiple trials. Studies on this smart drug suggest it could help those suffering from mild cognitive impairment and acute or chronic fatigue. Plus, it could protect the brain.
Despite offering so many benefits, not many persons know about Centrophenoxine. That is a shame. Not only because this nootropic could help many people out there. But also because it’s safe for everyday use. Read our Centrophenoxine review to know more about this nootropic supplement.
What Is Centrophenoxine?
Centrophenoxine is an acetylcholine supplement and one of the best nootropics out there. Acetylcholine supplements increase the neurotransmitter’s levels in the brain. They boost functions associated with the brain chemical, including memory, learning, cognition, and others.
Multiple studies and a few clinical trials have proven Centrophenoxine’s ability to boost cognitive function and protect brain health. It has also been proven helpful for patients with Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. [R]
Many Centrophenoxine users report experiencing high brain energy levels only after a single dose. The supplement also reduces acute or chronic fatigue, a debilitating condition that could hurt the quality of your life. It can also be used to clear brain fog.
Small wonder then that Centrophenoxine is legal in almost all developed nations. Doctors in Japan and the UK prescribe it to patients experiencing age-related memory loss. In the US and Canada, it’s sold as an over-the-counter dietary supplement.
Overview of Benefits and Side Effects
Before looking at what the researcher community and users have to say about this smart drug, let’s have an overview of Centrophenoxine’s benefits and effects.
- Improves Memory
- Elevates Mood
- Is Anti-Aging
- Enhances Cognition
- … And Many More
- Moderate Depression
People with liver issues, depression, bipolar disorder, and seizure disorders are advised to avoid this drug. Consult with your doctor if you’ve any safety concerns.
How Does Centrophenoxine Work In The Brain?
Centrophenoxine is a combination of two chemicals. These include dimethyl-aminoethanol (DMAE) and para-chlorphnoxyacetic acid (PCPA). Among these chemicals, DMAE is extremely crucial to the way Centrophenoxine works.
Centrophenoxine primarily works as a precursor to DMAE. Once you ingest it, your body breaks it down into DMAE and PCPA. Having crossed the blood brain barrier, DMAE goes straight to the brain, where it increases acetylcholine levels. [R] [R]
Here are Centrophenoxine’s proposed working mechanisms:
- Raises acetylcholine levels in the brain. It increases the activity or release of choline in the brain. Choline, in turn, promotes the production of acetylcholine, which plays a key role in various aspects of brain function, such as memory, learning and thinking. [R]
- Strengthens the neurons’ antioxidant defenses. In an animal study, Centrophenoxine activated antioxidant enzymes in various brain regions. This enables it to prevent memory and cognitive decline. [R]
- Protects the brain by reducing oxidative stress in multiple regions. It does that by reducing the accumulation of lipofuscin, the age pigment which causes waste in the brain and brown liver spots on the brain. [R]
- Increases glucose and oxygen uptake. Centrophenoxine increases the brain’s glucose uptake by supplying it with more energy. It enhances its oxygen uptake by promoting blood flow throughout the brain and neurons.
Keep in mind that Centrophenoxine’s exact working mechanisms are still under investigation.
Centrophenoxine is one of few nootropics that come with proven benefits. It could improve memory, reduce oxidative stress in the brain and boost cognitive functions. You could also count on this smart drug to improve mental clarity and protect nerve cells from dying.
This nootropic supplement has also been proven to reverse some of the signs of brain aging, especially when taken in high doses for a short period. On the other end, users who stick with a low dose can expect Centrophenoxine to act as a neural enhancer.
Here are the proven Centrophenoxine benefits:
- Improves Memory
- Reverses Aging Signs
- Enhances Mood
- Boosts Cognition
- Increases Life Span
- Protects The Brain
Let’s expound on these benefits.
Improved memory is one of the most well-known benefits of Centrophenoxine. This smart drug does this by stimulating the release and activity of acetylcholine in the brain. The resulting increase in acetylcholine levels enhances memory as well as learning.
Yet another way Centrophenoxine boosts memory is increasing communication between neurons. The resulting improvement in the exchange of information between brain cells helps them store and retrieve long-term memories. It also reduces the risk of age-related cognitive decline.
Alpha GPC is another nootropic that enhances memory. But medical studies suggest that Centrophenoxine is even more effective and provides better results in older adults. We’d suggest you prefer this nootropic over Alpha GPC.
Centrophenoxine employs three mechanisms to reverse aging.
Firstly, it reduces the accumulation of lipofuscin (age pigment) in the brain. Lipofuscin is notorious for exposing the brain to the effects of aging. Studies have shown that lipofuscin makes specific brain cells vulnerable to oxidative damage (in the short term) and death (in the long term). [R] [R]
Secondly, this smart drug reverses the damage caused by the oxidation of fat. Oxidation of fat in the brain’s cell membranes is associated with various types of dementia, including Alzheimer’s. It is also linked with neurodegeneration and age-related cognitive decline. [R]
Thirdly, the nootropic is a powerful antioxidant. This makes it an aggressive enemy of radicals responsible for age-related deterioration. Centrophenoxine is also capable of repairing damaged cells and flushing out toxins capable of damaging the brain. [R]
Animal studies have shown that Centrophenoxine possesses the ability to decrease anxiety levels. This is probably due to the antioxidant effect of this nootropic. Eating food rich in antioxidants has been shown to reduce the symptoms of various anxiety disorders. [R] [R]
Antioxidants decrease anxiety by spurring the release of serotonin and dopamine. Both these ‘feel good’ hormones are famous for their ability to keep your anxiety levels in check. Almost all antidepressants target these two brain chemicals to manage anxiety.
Bromantane is another nootropic that improves mood. But it follows a different mechanism to that of Centrophenoxine. Bromantane reduces specific anxiety symptoms – muscle tightness, dread, edginess– by enhancing GABA-ergic mediation.
Boosts Cognitive Functions
Centrophenoxine acts as a precursor to DMAE (dimethylaminoethanol) in the brain. DMAE boosts choline production to increase acetylcholine levels in the brain. But it doesn’t stop at that. DMAE is also responsible for reducing oxidative stress and the build-up of age pigment (lipofuscin).
By reducing the accumulation of age pigment, DMAE decreases its ability to hurt cognitive functioning. The removal of age-pigment also prevents brain damage and reduces the speed of the aging process, especially in older people. This, in turn, boosts cognitive functions.
Centrophenoxine follows one more route to enhance cognition. It increases the availability of glucose and oxygen to the brain. Research has shown that increased oxygen levels in the brain improve cognition, especially in the elderly. [R]
Increases Life Span
In a clinical trial on rat brains, Centrophenoxine enhanced the mouse’s lifespan by up to 50%. Brain cell membranes consist of fat, which gets oxidized with age. The oxidation process leads to the accumulation of free radicals, especially as you grow old. [R]
However, Centrophenoxine removes the age pigment and other free radicals from the brain. By doing this, it doesn’t allow cellular waste to accumulate in the brain. This keeps the mind clean. And as the abovementioned study shows, it also increases lifespan.
The researchers conducting the study claimed that the rat brains were ‘rejuvenated’ after the study. Some of the parameters related to their brain’s functioning returned to the values found in adult and young animals, a hugely encouraging sign.
Protects the Brain
Centrophenoxine reduces lipofuscin levels to protect the brain. Lipofuscin is a waste product that resides inside neurons and other cells. It is more commonly known as age-pigment. It is formed due to reactions involving oxygen-derived free radicals.
Lipofuscin build-up is linked to multiple types of dementia, including Alzheimer’s disease. Researchers state that this waste product also causes aging. Even more worrying is that lipofuscin levels inside the neurons and other body cells increase with age.
That’s precisely what Centrophenoxine prevents. In one animal study, this nootropic successfully reduced lipofuscin levels in the brain. The removal of lipofuscin helped rejuvenate the rat brain, improving various parameters and decreasing the risk of brain disease.
Start with a low dose. Observe how your body reacts to Centrophenoxine and see if there are any worrying symptoms. You can always increase the dosage to get the health benefits mentioned above after being comfortable with how this drug works.
It’s recommended to take 400 mg of Centrophenoxine daily, in 1 to 2 doses. We advise you to take this smart drug with food. You can also mix it into a drink such as lemonade. Acting on this advice will help you enjoy a better taste. It will also enable your bloodstream to absorb it quickly.
Some people suggest taking up to 1000 mg. They are those who have grown resistant to this supplement. Now they aren’t as sensitive to low (or optimal) dosage as anyone who just started taking this supplement. Learn from their mistake and stick to the recommended Centrophenoxine dosage.
Try not to take this smart drug before bedtime. If you take it just before you’re going to sleep, Centrophenoxine might end up disrupting your sleeping patterns. To avoid such a scenario, we recommend taking this supplement with your first meal of the day.
How To Take Centrophenoxine?
Avoid taking Centrophenoxine at the same time as any other choline supplement. Or any nootropic supplement that has a choline-related mechanism, such as anticholinergic drugs and/or choline inhibitors. Otherwise, an unpredictable interaction may happen.
However, if you intend to take it with another choline supplement, take both drugs at least two hours apart from each other. Those of you with reduced cognitive function might benefit from stacking Centrophenoxine with Alpha GPC or DMAE.
That is because all three supplements can potentiate each other’s effects. Centrophenoxine directly increases acetylcholine levels in the brain. Alpha GMC and DMAE work to boost choline levels, which, in turn, will form acetylcholine.
Centrophenoxine Side Effects
Consult your doctor for medical advice before taking Centrophenoxine. Research has shown that high dosages of this supplement can cause liver damage. People who already have liver issues are more vulnerable to this severe side effect.
People with epilepsy or bipolar disorder should also do their due diligence before taking this drug. One study involving these individuals saw Centrophenoxine triggering seizures. Anybody with these medical conditions should take expert advice before taking it.
The same advice goes for women who are pregnant or planning on getting pregnant in the near future. They should also consult their physician before taking Centrophenoxine as we don’t know how this supplement will affect the child’s development.
Some of the more common side effects of Centrophenoxine include:
- Stomach trouble
- Drowsiness and confusion
- Headache and/or insomnia
- Moderate depression
- Heightened Blood Pressure
Feeling these effects? It’s a signal to lower the dosage. If the problem persists, consult your doctor to provide medical advice. Stop using the drug if the issue doesn’t go away.
Having discussed what Centrophenoxine is and how it works, it’s time we turn our attention to other drugs and supplements that could potentiate its effects.
Centrophenoxine will offer enough benefits on its own but stacking it with other supplements that could enhance its benefits will help you enjoy even better results.
- Centrophenoxine Piracetam Stack. Piracetam is a synthetic derivative of the neurotransmitter GABA. It makes an excellent stack option with Centrophenoxine because both offer similar benefits.
- Centrophenoxine Noopept Stack. Noopept provides all the benefits that Piracetam could offer, and that too in relatively smaller dosages. As such, stacking Noopept with Centrophenoxine is a no-brainer.
- L-Theanine Centrophenoxine Stack. A major component of black and green tea, L-Theanine can promote anything from relaxation to arousal. It also improves mental alertness, concentration levels, and reaction time.
You could also stack Centrophenoxine with Aniracetam to enhance cognition, mood, and creativity.
Where Can I Buy Centrophenoxine?
Unlike some nootropics that you can only buy with a prescription, Centrophenoxine can be purchased over the counter in the US. It’s legal to buy as much as you need. We’d suggest you order the stock that could last a month because who knows you may get a discount.
PureRawz is our favorite place to buy Centrophenoxine powder. The site offers a 30-day moneyback guarantee and a 100% satisfaction guarantee. You also get publicly available lab reports to verify that the drug you’re buying is safe and effective.
Frequently Asked Questions
Users report experiencing a gentle brain energy boost, increased alertness, and a feeling of well-being after taking Centrophenoxine first thing in the morning. They note how they’re able to recall things a bit easier, even when they’re in a stressful situation.
DMAE is one of the ingredients of Centrophenoxine. It is found naturally in many types of fish, such as herring, sardines, and anchovies. Beans and green vegetables also contain trace amounts of DMAE.
Also, unlike Centrophenoxine, DMAE cannot cross the blood brain barrier. But it can treat aging skin, according to a study published in the American Journal of Clinical Dermatology. That is something Centrophenoxine cannot do. [R]
In conclusion, Centrophenoxine is one of the best nootropics right now for improving cognition, anti-aging, and improving memory as a whole. Sticking to a low dose can completely transform your mental well-being in a short time.
Otherwise known as Meclofenoxate, it can elevate your mood and protect the brain from various neurological disorders, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS).
If you’re looking for 100% pure, high-quality Centrophenoxine, we recommend you buy it from Pure Rawz. They’re one of the most reliable brands when it comes to nootropics, drugs, and health and fitness supplements.
It goes without saying that if you’ve any questions about Centrophenoxine, or nootropics in general, feel free to leave your comment below.