Cardarine, a metabolic modulator, is a compound that is known for its purported benefits such as weight loss, blood sugar levels, physical endurance, and improved metabolism.
If you are not familiar with Cardarine and want to learn more about this interesting compound keep reading the blog. In this blog, we will let you know more about Cardarine. We’ll explain everything about Cardarine from its potential benefits to its side effects and dosages.
We’ll also give you insight into its legal status and discuss its best vendors. So buckle up, as we are going to jump into this blog!
What is Cardarine?
Cardarine is a PPAR (Peroxisome Proliferator-Activated Receptor) receptor agonist, meaning it activates specific receptors in the body.
PPARs are a group of nuclear receptors that promote gene expression. It affects how your body uses and stores energy.
Cardarine and other PPARs like GW0742 are believed to improve fat metabolism and enhance blood sugar levels. The metabolic modulator also helps in weight loss and improves overall endurance.
How does Cardarine (GW1516) Work?
Cardarine binds to and activates the PPARδ pathway and impacts various metabolic processes, specifically those associated with fat metabolism and energy expenditure. By activating the PPARδ pathway, Cardarine enhances the body’s ability to utilize fat for energy and reduce body fat while increasing muscle production. [1]
Potential Benefits of Cardarine
Cardarine is believed to have multiple benefits. It can help treat obesity and various cardiovascular problems. A few of its other purported benefits are listed below.
May Treat Diabetes
Studies have found that Cardarine might be beneficial in the treatment of type 2 diabetes. In a study involving animals, Cardarine has been shown to improve blood sugar and insulin levels in gestational diabetes conditions [2]
Gestational diabetes (high blood sugar in pregnant women) can cause serious problems during delivery. Besides, other research has found that Cardarine helps in wound healing in diabetic subjects.
Help with Fat Loss
One of the major benefits of Cardarine is that it reduces body fat. Cardarine belongs to the class of metabolic modulators. These modulators influence the metabolic pathways and modify the body’s metabolism. [3]
Metabolic modulators stimulate the metabolic pathways to break down the fatty acids for energy, through a fat oxidation process.
The fat oxidation process allows your body to store less fat. Another way these modulators work is by burning the fat. The whole process occurs in mitochondria, a place where fatty acids are converted into energy.
One of the interesting facts about metabolic modulators is that they do not affect other cardiovascular functions such as blood flow while converting fatty acids.
Enhance Blood Lipid Levels
Cardarine activates the Peroxisome proliferator-activated receptors (PPARs). PPAR receptors might influence the hormones that regulate blood sugar and blood lipid levels in the body.
The amount of fats and cholesterol present in the bloodstream is referred to as blood lipid levels. Blood lipid levels mainly include Low-Density Lipoprotein (LDL), often called “ bad cholesterol” and High-Density Lipoprotein (HDL) known as “good cholesterol”. [4]
When the level of LDL is high, it leads to plaque build-up in arteries, which is not good for health. Blood lipid levels also include Triglycerides. When Triglycerides are high they can increase the risk of It is a type of fat that can increase the risk of heart disease.
When the blood lipid levels are not balanced they cause dyslipidemia (the condition that contributes to heart disease). Cardarine might have the potential to maintain and enhance blood lipid levels.
Potential to Enhance Sports Performance
A least known benefit that people have reported for Cardarine is its ability to improve athletic performance.
As Cardarine burns body fat and uses the stored fat for energy, many users claim that it enhances endurance, boosts stamina, and improves workout capacity and cardiovascular performance.
A study in 2015 on mice found that Cardarine has a positive impact on exhaustive running performance. [5]
Potential Side Effects of Cardarine
- Liver health problem
- Dizziness and headaches
- Cancer
Recommended Dosage for Cardarine
When it comes to dosage, you will find various ranges. The most discussed range is 2.5 mg – 10 mg. Some users even took 10 mg – 20 mg.
It is important to note that there are no authentic sources that back that study about the dosage. So make sure to consult your healthcare provider before taking the dose.
Disclaimer:
The information provided is for informational purposes only and should not be considered medical advice. Readers should consult with a healthcare professional before using Cardarine or any other supplement.
Top Vendors for Cardarine
Cardarine is a kind of compound that is banned by the WADA and FDA for various reasons. The research on this product is also very limited. However, people still buy the product for research and various other purposes.
If after reading the blog you’ve developed an interest in this compound and want to purchase it, then here are the vendors you would want to consider.
| Vendors | Price Range | Customer Feedback | Verdict |
| Purerawz | $34.57 | Exceptional | Purerawz has been around for years. The online vendors are famous for their reputable and authentic products. |
| Behemothlabz | $46.89 | Satisfactory | They offer you the first and third-party tested Cardarine along with the COA (certificate of analysis). |
| RCD.bio | $46.89 | Excellent | The vendor offers reliable products. Their customer feedback also shows how incredible they are. |
| Science. bio | $49.99 | Exceptional | An impressive online store that offers you Cardarine at flexible prices. Their products are lab-tested. |
| Iron mountain labz | $70.48–$125.48 | Satisfactory | Their products are 99% tested for quality and they offer incredible customer support. |
On the Whole:
Cardarine, a metabolic modulator and PPAR receptor agonist is thought to burn body fat and regulate blood sugar levels. It may also boost metabolism and improve blood lipid levels by activating specific pathways. The compound may also help treat type 2 diabetes.
There is still not a strong study that suggests that Cardarine is beneficial for human consumption!
FAQs
1. Does Cardarine Affect My Hair Growth?
There is not a 100 % study that says that Cardarine causes hair loss. However, some purported research suggests that Cardarine might cause hair loss.
2. What Does Cardarine Do?
Cardarine binds with the PPAR receptors in the body and aids in fat burning. The compound also converts the stored fat into energy and boosts metabolism.
3. Is Cardarine SARM?
No, Cardarine is not a SARM and several people may think of it as a SARM. Cardarine is a PPAR receptor agonist that is believed to improve blood lipid levels, treat diabetes, and enhance metabolism and endurance.
4. Will Cardarine Help You Lose Weight?
Yes, Cardarine can help in weight loss. Cardarine enhances the body’s ability to burn fat and increase metabolism. It activates the metabolic modulators that stimulate the metabolic pathways that break down the fatty acids.
5. Does Cardarine Affect Muscle Mass?
Cardarine does not directly increase muscle mass. Instead, it helps preserve it during fat loss by targeting stored fat. Plus, its endurance-boosting effects have made it popular among athletes and various bodybuilders.
6. How Long is the Cardarine cycle length?
When using Cardarine with a SARM like Ostarine ( a known stack for the cutting phase), It might run for 6 weeks. There is no need for any cycle if you use Cardarine alone. That is because Cardarine has minimal side effects.
7. Is Cardarine Legal?
While researchers at the FDA have still not given this substance the “okay” for human consumption. Currently, this supplement is classified as a research chemical, meaning that people can buy it for personal research.
Reference
- Kintz, P., Ameline, A., Gheddar, L., & Raul, J. (2020). Testing for GW501516 (cardarine) in human hair using LC/MS–MS and confirmation by LC/HRMS. Drug Testing and Analysis. https://doi.org/10.1002/dta.2802
- Zhou, J., Zhe, R., Guo, X., Chen, Y., Zou, Y., Zhou, L., & Wang, Z. (2020). The Role of PPARδ Agosnist GW501516 in Rats with Gestational Diabetes Mellitus. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Volume 13, 2307–2316. https://doi.org/10.2147/dmso.s251491
- CARDARINE: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews. (n.d.). Www.webmd.com. https://www.webmd.com/vitamins/ai/ingredientmono-1648/cardarine-%5Bfast-facts%5D
- Olson, E. J., Pearce, G. L., Jones, N. P., & Sprecher, D. L. (2012). Lipid Effects of Peroxisome Proliferator-Activated Receptor-Δ Agonist GW501516 in Subjects With Low High-Density Lipoprotein Cholesterol. Arteriosclerosis, Thrombosis, and Vascular Biology, 32(9), 2289–2294. https://doi.org/10.1161/atvbaha.112.247890
- Chen, W., Gao, R., Xie, X., Zheng, Z., Li, H., Li, S., Dong, F., & Wang, L. (2015). A metabolomic study of the PPARδ agonist GW501516 for enhancing running endurance in Kunming mice. Scientific Reports, 5(1). https://doi.org/10.1038/srep09884
3 Responses
Should Cardarine be taken with food, or does it matter?
Doesn’t matter. I take it on an empty stomach first thing in the morning when I’m on cycle.
I don’t do metrics, is .50 ml equal to 10 mg? Thanks…