Have you ever wished there was a way out of the frustrating loop of sexual health problems that deals with the aspects of desire and fulfilment? Finding that one thing that makes a long-term relationship work, dealing with erectile dysfunction, or fighting the silent war against a declining libido due to age or medicine is something many people struggle with. Stop worrying; the answer could be right around the corner. Has the idea of a breakthrough that addresses the specific needs of men and women ever crossed your mind? It would go beyond the limitations of conventional treatments. A synthetic peptide called PT-141 has recently come to light, and it promises to revolutionise sexual health. Let’s dig into the science and find out how PT-141 is changing the story of sexual health and providing hope to those who want a better intimate life.
Introduction
Palatin Technologies’ groundbreaking PT-141 stands out as a potential answer to the problem of how to improve men’s libido. Although it shares an ancestor with the famous MTII, this variant stands out due to the substitution of a -OH group at the C-terminus for a -NH2. It is worth mentioning that PT-141 has shown a success rate of over 80% in causing erections, even when conventional phosphodiesterase-5 inhibitors such as Sildenafil (Viagra) failed to do so. Unlike medications like Viagra, PT-141 is administered through a nasal atomizer. By binding to MCR3 and MCR-4 receptors in the brain, it triggers libido and penile erections in the brain.[R]
Product Information:
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Experience a new level of intimacy with Purerawz’s PT-141, now in a convenient peptide form. The benefits of injecting PT-141 are obvious. The peptide’s benefits are accelerated to new heights with the subcutaneous injection method, which guarantees accuracy and control. Subcutaneous injections allow the magic to flow directly and efficiently into your bloodstream, unlike other methods such as oral or nasal administration. On top of that, you can adjust the dosage to your preference because the injection process puts you in charge. Because it is so easy to use, the 10 mg vial of PT-141 from Purerawz has quickly become a favorite among users.
| PT-141 | |
| CAS Number | 189691-06-3 |
| Molar Mass | 1025.182 g·mol−1 |
| Chemical Formula | C50H68N14O10 |
| IUPAC Name | (3S,6S,9R,12S,15S,23S)-15-[(N-Acetyl-L-norleucyl)amino]-9-benzyl-6-{3-[(diaminomethylidene)amino]propyl}-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxylic acid |
How does PT 141 Work?
Palatin Technologies’ PT-141 is a new approach to treating erectile dysfunction in both sexes. We’ll examine how it works for both sexes in detail.
When compared to more conventional options, such as Viagra, PT-141 offers men an alternative. Instead of the usual suspects, it messes with the brain’s MCR-3 and MCR-4 receptors. More than 80% of men who had no luck with previous treatments saw improvements after making this adjustment, indicating a rapid and robust response. Optimal aspect? Waiting is not an issue with PT-141. It takes effect in a matter of minutes and remains in effect for as long as eight hours. This is a game-changer, particularly for the seasoned gentlemen, because you don’t even have to get busy to start the party.
Alright, ladies, let’s move on. With the help of the female brain’s MCR-3 and MCR-4 receptors, PT-141 is a natural matchmaker. Instead of a direct strike to the blood vessels, a deft neural maneuver is employed. Results from studies on both furry and non-furry subjects (humans and animals) demonstrate that PT-141 is safe and effective in increasing blood flow to the areas that matter most to women. And what was the outcome? A revolutionary solution for the 30 million American men who suffer from erectile dysfunction. As far as sexual health products go, PT-141 looks like a trustworthy companion, providing men and women with pleasant and effective options. [R]
PT 141- Benefits:
PT-141 has undergone extensive laboratory and research use, not only in animal subjects but also in clinical research involving the human body. This exploration aims to understand its potential health benefits, particularly in the context of sexual health Below, we have compiled some of these benefits:
• Increased Sexual Desire, Genital Arousal, and Satisfaction in Women
Although PT-141 (bremelanotide) has long been associated with male sexual health issues, it is now paving the way for women to have their own unique set of problems addressed. We should all be concerned about our sexual health, and this synthetic peptide is helping to fight female sexual arousal disorder. Results from the first round of bremelanotide trials in premenopausal women with a single dose were encouraging: they reported higher levels of sexual desire, better genital arousal, and greater satisfaction with their sexual arousal levels one day after treatment. The results of this study suggest that bremelanotide may be useful in improving women’s sexual health, which could lead to additional investigation in the future.[R]
• Treatment Option for Erectile Dysfunction in Men
There is hope for those who are struggling with erectile dysfunction; PT-141 is one such medication. When administered intranasally, this chemical has demonstrated exceptional tolerance in both healthy individuals and those battling erectile dysfunction. It is well-known for its erectionogenic effects in animals and humans. Crucially, there are no major cardiovascular risks associated with PT-141 use. Penile rigidity and tumescence are improved in both healthy volunteers and those with erectile dysfunction, and the improvement is dose-dependent. Based on these results, PT-141 shows great promise as a treatment option for erectile dysfunction in men, which bodes well for men’s sexual health generally.[R]
• Treatment of Hypoactive Sexual Desire Disorder
Maybe you’re in your twilight years and ready to spice up your sex life; maybe you want to be the most amazing partner you can be. It’s normal for people of all ages to look for methods to improve their sexual encounters. Hypoactive sexual desire disorder (HSDD) is a long-term issue that affects as many as 10% of American women. A lack of sexual fantasies or thoughts, which characterizes this condition, can cause emotional pain for the sufferer. Factors such as duration, intensity, and frequency have contributed to a more nuanced understanding of HSDD. Bremelanotide or PT-141 is a breakthrough in the treatment of low desire, which can be caused by several things, including medical issues and psychosocial factors. Premenopausal women with HSDD showed marked improvements in sexual desire and reductions in related distress after receiving this subcutaneously administered treatment, according to two extensive clinical trials.[R]
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• Superior Efficacy Compared to Viagra
If you’re seeking a solution to your erectile dysfunction (ED) that goes beyond what Viagra® can provide, PT-141 could be the one for you. After being subcutaneously administered to both healthy men and women with erectile dysfunction who had an adverse reaction to Viagra, this cyclic heptapeptide melanocortin analog was studied. When compared to Viagra®, which only produced a good erection about half the time, PT-141 worked much better. Patients with erectile dysfunction who were given 4 or 6 mg of PT-141 while also receiving visual sexual stimulation showed statistically significant improvements, whereas healthy subjects demonstrated statistically significant erectile responses at doses greater than 1.0 mg. People with erectile dysfunction (ED), especially those who do not respond well to PDE5 inhibitors like Viagra, may have a new, safer option with PT-141, which was well-tolerated in both trials.[R]
There are other benefits for PT 141. A few of the label claims have been reported by users:
• Age 57 User Reports Benefits of PT141, Tadalafil, and Oxytocin
A 57-year-old user reported taking a PT141 injection and experienced mild dizziness for an hour or two. However, shortly after, persistent and strong erections occurred, even waking up with them in the middle of the night. This boosted confidence, and the user takes the injection every 72 hours, about 0.15ml each time. The effects were felt within 30 minutes. The user also mentioned taking 20mg of Tadalafil daily, as advised by a urologist, to always be ready for sexual activity. Additionally, Oxytocin was added for potential social benefits.[R]
• Addressing Bodybuilding Anabolic Steroid Libido Issues
A bodybuilding enthusiast recently shared their experience of grappling with libido issues commonly linked to anabolic steroid use. To address this concern, the individual integrated PT141 (Bremelanotide) into their routine, reporting noteworthy improvements, including heightened desire and enhanced sexual satisfaction. This revelation underscores the potential role of PT141 in mitigating the adverse effects on libido associated with anabolic steroid usage within the bodybuilding community.
PT-141 Side Effects:
Both men and women taking PT-141, especially at doses of 5, 7.5, or 10 mg, reported similar common side effects. About 45% of healthy males and presumably females experienced flushing, somnolence, nausea, vomiting, and headache. Notably, in the 0.3–3 mg dose range, only flushing was observed. Vomiting, identified as the main issue, occurred after some doses but either went away on its own or responded well to ondansetron, a medication that helps with nausea. Importantly, there were no significant changes in blood pressure, heart rate, or ECG evaluations compared to before taking PT-141.[R] [R]
Despite the mild side effects like nausea and flushing, the overall safety profile looks encouraging, offering hope for addressing concerns related to sexual desire in both men and women. Always consult with your healthcare provider for personalized advice.
PT-141 Dose:
For males, PT-141 demonstrated safety and tolerability at varying doses. Single doses of up to 10 mg were administered to healthy male subjects, while patients with erectile dysfunction (ED) received doses of up to 6 mg.[R]
For female participants, all subcutaneous dose levels of bremelanotide were deemed safe and well-tolerated. Notably, a statistically significant increase in vaginal pulse amplitude (VPA) during visual sexual stimulation (VSS) was observed compared to baseline after the administration of the 3.0 and 5.0 mg doses. This suggests a potentially positive impact on physiological responses in females, emphasizing the safety and efficacy of bremelanotide in addressing sexual arousal concerns.[R]
In forums, it has been recommended to inject the peptide for 1-2 hours before engaging in intimate activities.
Purerawz introduces a convenient solution with PT-141 available in peptide form. Each vial is precisely formulated with a total of 10mg of PT-141, offering an easily adjustable dosage based on individual needs. The packaging provides a straightforward and accurate approach to dosing. It is recommended to start with a lower dosage and customize it according to personal goals, allowing for a gradual adaptation to the peptide. Before incorporating PT-141 into your routine, it is advisable to consult with a healthcare professional for personalized advice on safe and effective usage.
FAQ
What is PT 141 half-life?
PT-141 has a half-life of 2.7 hours, which can be anywhere from 1.9 to 4 hours, and a time-to-peak of 1 hour. This means that it is almost completely bioavailable.[R]
Is bremelanotide (PT 141) FDA-approved?
Yes, PT-141, also known as Vyleesi (bremelanotide), has received FDA approval. The U.S. Food and Drug Administration has approved Vyleesi to treat acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women.[R]
Where to Buy PT 141 Online?
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Conclusion:
This 2024 Purerawz review explores the complexity of PT-141, emphasizing its impact on sexual health in healthy male subjects and addressing sexual dysfunction. PT-141, a novel solution to treat sexual dysfunction, showcases its efficacy in enhancing sexual function, especially in male subjects. The product’s focus on alpha melanocyte-stimulating hormone and its role in promoting sexual intercourse and providing an enhanced erectile response is highlighted, making it a notable contender in the realm of addressing male sexual dysfunction.
This comprehensive exploration extends to the domain of female sexual dysfunction, where PT-141 emerges as a potential remedy for female hypoactive sexual desire. The review underscores PT-141’s influence on sexual behavior and its promising role in treating sexual disorders. Purerawz’s meticulous examination emphasizes the varied benefits of PT-141, positioning it as a versatile option for those seeking improvements in sexual health. With a focus on alpha melanocyte-stimulating hormone and its impact on both genders, PT-141 stands out as a noteworthy solution in the landscape of sexual well-being.