LGD 3033 Guide: Dosage, Results, Benefits, & More (2022)

LGD 3033, just like LGD 4033, is a selective androgen receptor modulator (SARM). Both help users put on lean muscle mass, increase muscle strength and endurance. Both are synthesized by the same company, Ligand Pharmaceuticals, with LGD 3033 being the next version of LGD 4033.

That’s where the similarities end. LGD 3033, unlike LGD 4033, is a ‘dry’ compound, meaning it carries no water weight. LGD 3033 is also said to be more bio-available than its predecessor. Your body can absorb more from the supplement to achieve your fitness goals.

In a nutshell, if you want rapid muscle gains, quick weight loss, and a swift increase in your stamina, you ought to try LGD 3033. That isn’t to say that this supplement doesn’t have any side effects – we have discussed all of them in much detail below.

In case you’re interested in buying this supplement after reading our review, one of the highest quality sources out there is PureRawz. All of their products come with independent 3rd party lab reports, so you may trust them to be safe.

What Is LGD 3033?

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LGD 3033 is a selective androgen receptor modulator (SARM). It was initially designed and developed to prevent and cure muscle atrophy, the medical term for muscle wasting. The supplement may also help ease symptoms of osteoporosis by building bone density in users.

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Bodybuilders and athletes have been using this supplement for quite some time due to its impact on muscle size. Anecdotal evidence and multiple research pieces also confirm that LGD 3033 gives the muscles a fuller look by increasing their water retention.

However, the benefits of LGD 3033 aren’t limited to muscle mass growth. This SARM might also help users build endurance, increase bone density and decrease body fat. Multiple users who have used both claim its side effects are much milder than LGD 4033. [R]


Before we dive deep into what the scientific community has unearthed about LGD 3033, let’s first have a quick glance at its proven benefits and side effects.


  • Improves Stamina and Endurance
  • Encourages Fat Loss
  • Helps Build Muscle
  • Enhances Libido

Side Effects

  • Not Approved For Human Use (Yet)
  • Suppresses Testosterone During Cycle
  • May Have Detrimental Effects On Liver Function

While LGD 3033 suppresses your body’s natural production of testosterone, you can restart the production with a post-cycle therapy.

In October 2017, the US Food & Drug Administration issued a warning stating that SARMs, including LGD 3033, are not legitimate dietary ingredients. [R]

Both the US Anti-Doping Agency (USADA) and the World Anti-Doping Agency (WADA) have prohibited all athletes from using LGD 4033 (both in-competition and out-of-competition). [R]

That being said, SARMs are legal to buy and own.

Make sure you’re buying LGD 3033 from a vendor selling it for research purposes only, because it’s illegal to sell SARMs for human consumption. If you’re looking for a good LGD 3033 source then read our article on the best SARMs for sale on the market right now.

How Does LGD 3033 Work?

LGD 3033, like most other SARMs, selectively binds to your body’s androgen receptors. The term ‘selective’ deserves your attention as it’s what differentiates SARMs from steroids. While steroids target all muscles, SARMs like LGD 3033 only target the skeletal muscle, sparing other tissues. [R]

Once it attaches to the skeletal muscle, LGD 3033 mimics the effect of naturally produced testosterone to stimulate the muscle tissue to grow (or ‘bulk up’) in response to training. That’s when muscle mass, recovery, and more will begin to increase.

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LGD 3033 also facilitates the nitrogen and water retention of muscles, helping them achieve a fuller look. Its highly specific working mechanism enables the effects of LGD 4033 to become visible after a few days of use, in contrast to other SARMs whose effects take weeks to materialize.

LGD 3033 Benefits

LGD 3033

There are various benefits of LGD 3033 use: muscle mass growth, increased bone density, and fat loss enhancement. Anecdotal evidence also credits this SARM for fuller-looking muscles and shorter time than other SARMs to deliver results.

Here are key benefits of LGD-3033:

  • Rapid Muscle Growth
  • Swift Fat Loss
  • Increased Bone Density
  • Improved Libido
  • Enhanced Stamina

The best thing about most of these benefits is that they’re research-backed – you don’t have to rely on anecdotal evidence to believe in them.

Let’s discuss all these benefits in more detail:

1. Enhances Muscle Growth

Research has shown that SARMs like LGD 3033 enhance muscle growth. They do so by binding to the body’s androgen receptors, mimicking the effects of testosterone, and stimulating the muscle tissue to strengthen and bulk up. Best of all, all this happens in a matter of few hours. [R]

This makes LGD 3033 ideal for bodybuilders who have tried multiple supplements in vain to put on lean muscle mass. It also makes this supplement perfect for anyone who wishes to make the most of their gym time to build muscles. In fact, we’d go so far as to say that LGD 3033 is one of the best SARMs for muscle growth and bulking on the market right now.

2. Increases Bone Density

At the time of writing, LGD 3033 is being investigated as a treatment for osteoporosis, a bone disease that makes you lose bone strength and mass. Osteoporosis mainly develops without any signs, making it difficult to discover until the latter stages, when it starts causing painful fractures. [R]

The good news is that LGD 3033 has been showing promise in the studies. One study has found that repeated oral doses of this supplement were far more effective than traditional treatments for increasing the mineral bone density in the subjects, both in the femur and the spine. [R]

3. Increases Libido

According to a study carried out on model rats, LGD 4033 successfully enhanced the male-directed sexual preference among the sexually experienced female rats, raising hopes that the supplement might also improve the libido among human users. [R]

The study’s researchers relied on the results to conclude that LGD 3033 might a) stimulate certain aspects of female sexual behavior and b) might help women dealing with sexual desire disorders. The results were compiled after the study’s subjects were given oral doses of LGD 3033 for seven days.

If you were to take LGD 3033 combined with a libido boosting supplement like Male Extra, for example, this would be a great way to easily double, triple, or even 10x your existing libido.

4. Facilitates Fat Loss

Since it’s an established fact that LGD 3033 helps build muscle – even USADA in its paper against SARMs gives the nod to this, one can draw a straight line between an increase in muscle mass brought about by LGD 3033 and a decrease in body fat. Here’s why we’re so sure. [R]

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Health experts tell us that one pound of muscle consumes somewhere between 75 and 150 calories per day. Unless you’re consuming extra calories to feed them, the added muscles will burn your body fat to generate energy for their own consumption, facilitating fat loss. [R]

5. Improves Stamina

One of the most vital benefits of LGD 3033 is that it builds stamina among users. Most of them report feeling a sudden burst of energy, stamina, and strength within a few hours of taking this supplement’s first dose. This helps them put in more effort in the gym. [R]

Dosage & Cycle Guidelines

muscle athlete holding weights

Since LGD 3033 has a half-life of up to six hours, you cannot take it once a day and expect to get the benefits. You have to take this supplement two to three times a day. Only then would it help you build muscles, stamina, and endurance.

Here’s the recommended LGD 3033 dosage:

  • For beginners: 10 mg a day, divided into two to three doses
  • For professionals: 20 mg a day, divided into two to three doses

Here are the LGD3033 cycles based on what you intend to use it for:

Cutting CycleBulking CycleRecomping Cycle
20 mg/day
6 to 8 weeks
20 mg/day
6 to 8 weeks
20 mg/day
8 to 10 weeks

Once you’ve completed the cycle, follow up with post-cycle therapy to help your body restart its natural testosterone production.

Side Effects

Most SARMs you see on the market pose side effects. Unfortunately, LGD 3033 is no different. Let’s have a quick overview of this supplement’s potential drawbacks: [R]

  • Possible Risk of Heart Disease and Liver Damage: At the time of writing, one law firm’s class action lawyers are investigating potential lawsuits on behalf of users who say they experienced heart disease and/or liver damage after using LGD 3033. [R]
  • Possible Cholesterol Increase: According to a Department of Defence advisory to armed services personnel, DOD civilians, and healthcare providers, SARMs may have a detrimental effect on cholesterol levels. [R]

One of the most common side effects of LGD 3033 is that it suppresses the body’s natural testosterone production.

That’s why many bodybuilders recommend using an aromatase inhibitor alongside LGD 3033 if your estrogen levels are skewed while using it.

This being said, you can mitigate most of these side effects by sticking to a moderate dosage and getting regular blood work done while you’re on the cycle.

Finally, if you have a family history of heart disease or high cholesterol, you may want to have your lipid profile done during the cycle to ensure your LDL and HDL levels are normal.

Is Post Cycle Therapy Required?

When it comes to SARMs, most people are concerned about whether or not they’ll have to use a post cycle therapy, or PCT for short. With a SARM like LGD-3033, this is generally best.

If you haven’t already, read our guide on SARMs PCT and how to do one. LGD-3033 is fairly suppressive to testosterone levels, so it’s important to do a good PCT post cycle to keep the gains you made.


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Anecdotal evidence, as well as multiple animal studies, confirm that LGD 3033 works. This SARM deserves your attention (and money) if you’re looking to put up lean muscle, build endurance, lose body fat, or increase libido. And that too in a short space of time.

Sure, LGD 3033 has its downsides, but that is something all SARMs have in common. Its major downside, that it has a short half-life (of almost 6 hours), can be easily countered by using LGD 3033 up to three times a day during the entirety of its cycle.

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Having said that, it must also be noted that more studies are needed on LGD 3033. Not only because we might not yet be fully aware of its long-term side effects. But also because there might be a few LGD 3033 benefits that we might not be aware of.

If you’ve liked what you’ve read and heard about this supplement, and intend to use it, we recommend opting for a respected 3rd party tested source, like Pure Rawz. All their products come with verifiable and independent 3rd party lab reports, so you can count on them to be safe.


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