When considering switching to a SARM (Selective Androgen Receptor Modulator) such as Ostarine, one often gets confused as there are various misconceptions associated with it.
One of the most controversial facts about Ostarine is that it suppresses testosterone. But wait—Is it true? Let’s make it clear and clear up your confusion!
“Ostarine is not as potent as other SARMs and does not suppress testosterone levels as much as other SARMs.” [1]
Is Ostarine Suppressive?
Yes, Ostarine, often known as MK 2866, does suppress testosterone, but its effects are milder than anabolic steroids. However, if used in high doses and for a longer time, the effect might get stronger. [1]
Users who have taken Ostarine have reportedly said that it slightly affects the hormonal balance, which in turn suppresses testosterone.
One study regarding Ostarine use has shown that it does not disrupt the development and balance of male hormones, including testosterone. [1]
Testosterone is the male hormone mainly produced in the testicles. It regulates various body aspects, including libido, bone mass, muscle mass, and fat distribution.

What Happens in Testosterone Suppression?
Testosterone suppression refers to the reduction of testosterone levels in the body. Lower testosterone production is not good for the body as it leads to muscle mass issues. It can also increase body fat, particularly around the abdomen area.
It is also believed that testosterone is important for maintaining bone density. Long-term testosterone suppression can affect bone mass and make bones more susceptible to fractures or osteoporosis.
Besides muscle mass and bone density, testosterone suppression affects sexual performance and causes difficulty in achieving or maintaining an erection. In addition to that, it can negatively affect mood and energy levels.
How to Avoid Ostarine Suppression?
Ostarine’s mild suppression of natural testosterone production can be avoided effectively. Here are some ways to potentially minimize or avoid it.
1. Use Lower Doses
- Using lower doses of Ostarine (e.g., 10-15 mg/day) may reduce the chances of significant suppression compared to higher doses (e.g., 20-30 mg/day).
- Always start with a lower dose and monitor how your body responds.
2. Shorten the Cycle Duration
- Using Ostarine for shorter cycles (e.g., 4-6 weeks) may help reduce the risk of suppression. Longer cycles increase the likelihood of disrupting the body’s natural testosterone production.
- Consider doing off-cycles to allow your body to recover.
3. Take Breaks Between Cycles
- After completing a cycle of Ostarine, it’s essential to take time off to allow your body to restore natural testosterone production. A typical cycle might involve 4-6 weeks of Ostarine use followed by 6-8 weeks off.
4. Implement a Post Cycle Therapy (PCT) Protocol
- A PCT protocol, which includes supplements or medications that stimulate natural testosterone production, can help restore hormonal balance after a cycle.
5. Avoid Long-Term Use
- The longer you use Ostarine, the more likely it is to suppress natural testosterone levels. Avoid using it continuously for prolonged periods, as the body may struggle to recover from such suppression.
6. Monitor Your Hormone Levels
- Regular blood tests can help you monitor your testosterone levels and other key markers during and after an Ostarine cycle. This will give you a better idea of whether you need to adjust your cycle or consider PCT.
7. Diet and Lifestyle
- Maintain a diet rich in nutrients that support natural testosterone production, such as healthy fats (e.g., omega-3s), vitamin D, zinc, and magnesium.
- Get proper sleep, manage stress, and engage in regular physical activity (especially resistance training) to support overall hormonal health.
Final Thoughts:
Yes, Ostarine may suppress testosterone levels to some extent. If used in high doses and for extended periods, the suppression can become more significant. However, there are very few users who have reported this problem. A majority of Ostarine users have described the SARM as relatively less suppressive than other SARMs.
References
- Vasilev, V., Nikolay Boyadjiev, Petar Hrischev, Fanka Gerginska, Slavi Delchev, Desislava Arabadzhiyska, Komrakova, M., Boeker, K. O., Schilling, A. F., & Katerina Georgieva. (2024). Ostarine blunts the effect of endurance training on submaximal endurance in rats. Naunyn-Schmiedeberg’s Archives of Pharmacology. https://doi.org/10.1007/s00210-024-03030-w