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Ostarine For Beginners: The Science-Based Guide to MK-2866 (Results, Studies, & More)

Ostarine, otherwise known as MK 2866 or Enobosarm, is one of the most popular SARMs on the market, which helps users rapidly build muscle.

In fact, Ostarine has exploded in popularity in the past several years, with dozens of athletes and weight lifters testing positive for MK 2866.

What does the research say, however? Is MK-2866 safe for human use, and does it actually lead to incredible performance enhancement?

In this article, we’ll explore the benefits of Ostarine, the best dosages, clinical studies, how much muscle users can gain, and much more.

What is Ostarine?

ostarine mk-2866 molecule structure

Ostarine, sometimes called MK-2866 or Enobosarm, is one of the most popular selective androgen receptor modulators, or SARMs for short, used to rapidly build muscle and lose fat.

MK 2866 has been around for decades, but was licensed to GTx Incorporated in 1997, and has since been undergoing clinical research. [R]

While the details of studies vary, most research agrees that Ostarine is a potent muscle-building compound with minimal side effects.

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This is why SARMs are often used by bodybuilders and athletes to enhance their performance, and attain supra-physiological feats of strength.

Overview of Pros & Cons

Before we delve deep into the clinical studies surrounding Ostarine and other SARMs, let’s take a brief look at the pros and cons of this SARM.

The benefits of Ostarine (MK-2866) include:

  • Increased Muscle Mass
  • Improved Bone Density
  • Very Fast Results
  • Backed By Ample Data
  • Faster Recovery Time
  • Rapid Fat Loss

The potential drawbacks include:

  • Can Have Negative Side Effects
  • Potentially Unknown Effects on the Body
  • Not Approved For Human Use (Yet)
  • More Data on Long-Term Side Effects is Required

While Ostarine has generally been shown to be safe in healthy individuals, more data is needed to determine if SARMs as a whole are safe long-term.

This being said, Ostarine presents enormous promise to be used as a way to treat cachexia (muscle wasting) in cancer patients, as well as other conditions, and is currently undergoing FDA trials.

Legality of SARMs

Ostarine, as well as other SARMs, are strictly prohibited by the World Anti-Doping Agency (WADA) for athletic use. So, if you’re an athlete and test positive for SARMs, you could be disqualified from competition. [R]

The USADA, or the United States Anti Doping Agency, has also banned SARMs from competition, so if you’re an athlete and get drug tested regularly, it’s highly recommended that you avoid SARMs.

That being said, SARMs are completely legal to purchase.

Many individuals order Ostarine for personal use, as it’s legal to sell as a “research chemical,” and end up taking it for bodybuilding.

How to Get Ostarine

The FDA and USADA have warned in the past about vendors who sell fake SARMs, which is why it’s so important to get them from a good source.

If you’re just skimming and want to get 99% pure Ostarine (MK-2866), tested by a 3rd party laboratory, then we recommend Science Bio.

Every batch of their SARMs is 3rd party verified by an independent laboratory, so you know for a fact that what you’re getting is real.

How Does Ostarine Work?

sarms androgen receptors

Similar to all SARMs, Ostarine works by binding to androgen receptors in your body, signaling muscles to rapidly start growing and repairing.

In other words, Ostarine begins working shortly after ingestion, and signals your body to pack on slabs of muscle in very short periods of time.

What makes Ostarine unique is that it’s selective in nature. In other words, it gives steroid-like effects, without aromatization. [R]

While Ostarine does not aromatize in the body, it must still be noted that this doesn’t necessarily make it safer than steroids—in fact, many have pointed out that aromatization is necessary for overall health.

Ostarine vs. Steroids

While SARMs may have unknown long-term effects on the body, we do know that they can give steroid-like effects in the short run.

Many users report gaining over 10 or 15 pounds of muscle in a very short period of time, while also burning off fat and increasing their strength.

It is for this reason that people love using Ostarine for bodybuilding—not only is it a powerful anabolic compound, but it’s also legal to buy and sell.

Benefits of Ostarine

Ostarine, otherwise known as MK2866, has a plethora of benefits for bodybuilders, which is why it’s such a popular SARM on the market.

The benefits of Ostarine include:

  • Rapid Muscle Growth
  • Enhanced Athleticism
  • Accelerated Fat Loss
  • Increased Bone Density
  • …and more

Ostarine has been proven many times through clinical studies to have a very beneficial effect on muscle growth and overall body mass index.

Rapid Muscle Growth

Perhaps the most well-known benefit of Ostarine is the fact that it causes rapid muscle growth in users who take it. In fact, this is one of the primary reasons that bodybuilders and athletes take Ostarine.

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One study, for example, conducted on 120 elderly people, found that even a dosage as small as 3mg per day led to significant muscle gains. [R]

This SARM in particular is known for having a strong effect on androgen receptors and is comparable to a low dosage cycle of steroids.

Enhanced Athleticism

It’s no secret that using Ostarine for bodybuilding is one of the main reasons why people choose to take Ostarine in the first place.

Users often report gaining over 10 pounds of muscle from an 8-12 week cycle of Ostarine, and often even more if they take higher doses.

Accelerated Fat Loss

Due to the anabolic nature of Ostarine, consuming MK-2866 also makes it far easier to lose fat, due to increase in your metabolic rate.

In other words, as the Ostarine works in your body to pack on more muscle, it will burn calories much faster to do so, meaning you can burn fat and build muscle at the same time, with relative ease.

Increased Bone Density

Not only does Ostarine increase lean muscle mass in users, but it also improves bone density, particularly in elderly individuals.

In fact, Ostarine is currently being researched in clinical studies as a potential way to prevent bone fractures in those with bone wasting diseases.

How to Take Ostarine

For the most part, Ostarine is taken in dosages between 10 mg to 25 mg, although some users and bodybuilders have taken over 50 mg per day.

The standard beginner’s dosage of Ostarine for bodybuilding is 10-15 mg per day—most users find that this is enough to get great results.

If you take more Ostarine than 25 mg per day, you will likely experience faster muscle gain and faster fat loss, however—but be careful.

Although Ostarine is well studied, for the most part, there is still a lot of uncertainty when it comes to the longer term side effects.

It’s also important to note that most of the studies conducted using Ostarine used dosages far less than the dosage that bodybuilders take. In fact, studies have shown that simply taking 3 mg of Ostarine per day will yield results.

Dosage For Bodybuilding

Most bodybuilders find that taking 15 mg of Ostarine is sufficient to yield rapid muscle gains and accelerated fat loss, however some take more.

If you’re a beginner, it’s recommended that you start by taking 15mg per day, at the same time each day, for an 8-week cycle to start.

More experienced users can take up to 25 mg per day, although there isn’t much research to support whether or not this is safe in the long-term.

Cycle Guidelines

For the most part, SARMs are taken in cycles of either 8 or 12 weeks, depending on the experience of the user and the desired results.

While On Cycle Be Sure to Increase Your Protein Consumption And Watch Your Macros Closely!

For Ostarine (MK-2866), it is recommended that you start by taking 15 mg per day for 8 weeks, and then follow this up with a post cycle therapy.

A standard Ostarine cycle might look something like this:

  • Weeks 1-8: Take 15 mg Ostarine per Day
  • Weeks 9-12: Begin Post Cycle Therapy
  • Weeks 12-16: Take A Break From SARMs

It’s generally recommended that users have at least 4 weeks in-between SARMs cycles, and ideally even longer than this. The more time you give your body to recover and reach equilibrium, the better.

Stacking Guidelines

Ostarine can also be stacked with other SARMs to drastically increase the effects. In fact, on a SARMs stack, users can expect to gain far more muscle mass, lose far more fat, and transform their overall body.

A good bulking stack would be:

Taken once per day, for 8-12 weeks, followed up by a PCT, this bulking cycle would yield incredible gains in muscle mass and overall strength.

A good cutting stack would be:

Taken daily for 8-12 weeks, again, followed with a post cycle therapy (PCT), this cutting stack would allow users to lose fat at a supraphysiological rate.

Ostarine Side Effects & Safety

ostarine side effects

While most individuals who use Ostarine (MK2866) don’t experience many side effects, there are some rare cases where they may occur.

The most common Ostarine side effects include [R]:

  • Decreased HDL Levels
  • Back Acne
  • Joint Pain
  • Increased Hunger
  • …and more

Again, most individuals don’t experience many side effects while taking Ostarine for bodybuilding, however more long-term research is needed.

Post Cycle Therapy

As with all SARMs, taking a post cycle therapy is highly recommended. The point of a post cycle therapy (PCT) is to restore natural testosterone levels.

There are two ways you can do this. The first is by taking a natural, over-the-counter testosterone booster as your post cycle therapy.

This will work well for most individuals, but for users taking a higher dosage of Ostarine, something like Nolvadex may work better.

In fact, we recommend you read our SARMs PCT guide for more info on how to run a proper post cycle therapy so for hormonal health.


All in all, MK 2866 is a powerful SARM which has been clinically proven to build muscle in users, even in dosages as low as 3mg per day.

If you do decide to use Ostarine for bodybuilding, be sure to get it from a good source that’s 99% pure and 3rd party verified, like Science Bio.

Always follow up any SARMs cycle with a post cycle therapy, and most importantly, monitor your blood work to assure safety.

If you have any questions, please let the Nanotech Team know and we will do our best to answer them in a timely fashion!

Frequently Asked Questions
❓ Is Ostarine Good For Bodybuilding?

Absolutely. Plenty of bodybuilders take Ostarine (MK-2866) as a way to enhance muscle growth and accelerate fat loss, particularly during a recomposition period. Ostarine is a potent SARM for muscle growth and fat loss, making it a bodybuilder's favorite to take.

❓ What Does Ostarine Do To Your Body?

Shortly after ingestion, Ostarine begins binding to androgen receptors in your skeletal muscles. In fact, within 24 hours, it begins signalling your body to build more muscle and accelerate its metabolism, leading to rapid fat loss, as well as a strength increase.

❓ What is Ostarine Used For?

Ostarine is a SARM which is typically used for building muscle and losing fat on a recomposition (or recomp for short). It is a very versatile SARM that can be thrown into a multitude of stacks, due to its ability to help men burn fat and build muscle at the same time.

❓ What's The Best Ostarine Dosage to Take?

Ostarine is typically taken in dosages between 10-25mg, although some users take up to 50mg per day. This being said, the best overall Ostarine dosage is going to be 25mg, because at this level you'll get a lot of muscle growth and fat loss with minimal side effects.

❓ Does Ostarine Require A PCT?

While plenty of users choose to ignore a post cycle therapy (PCT) after a cycle of Ostarine, it's typically best that you take a PCT after your Ostarine cycle to ensure you keep your gains and get your natural testosterone levels back to normal.

Nanotech Project Team

The Nanotech Project team is committed to providing the most accurate and up-to-date information about anabolics, nootropics, and bio-hacking as a whole.

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