Ready to kick frustration to the curb when it comes to working out without seeing the weight loss results you desire? Meet Purerawz Sublingual Tesamorelin Tablets, your game-changer in weight management! Bid farewell to the struggle and set off on a journey toward effective and sustainable weight management with Tesamorelin. This compound has recently gained FDA approval, making it a safe alternative to traditional anti-obesity drugs. Tesamorelin doesn’t just help with weight loss; it has also shown the potential to boost mental and cognitive well-being. Say hello to a new and effective approach to your weight management goals!
Tesamorelin is a synthetic version of a hormone-releasing factor found in the brain. The tablet is a man-made peptide containing all 44 amino acids of human growth hormone-releasing hormone (GHRH), with the inclusion of a trans-3-hexenoic acid group.
It was created by a Canadian company called Theratechnologies to address lipodystrophy, a medical condition characterized by abnormal or uneven distribution of fat in the body, a common condition in HIV-infected individuals.
After receiving FDA approval in November 2010, tesamorelin has been shown in two big studies to be beneficial in reducing extra fat and waist circumference around internal organs. There were further 26-week follow-up periods during which the good outcomes persisted.
Taking Tesamorelin tablets under the tongue has special benefits, especially when it comes to better bioavailability and quick effects. The sublingual route lets the peptide go straight to the cells that make up the membranes under the tongue, skipping the digestive system and the liver’s first metabolism. This makes it easier for Tesamorelin to get into the bloodstream, which could lead to a faster and more significant physiological response. The sublingual route also gives the peptide a more stable environment, which makes it more stable during absorption.
There are different ways to take Tesamorelin, but the sublingual tablet seems like the best option. The sublingual mucosa, which is under the tongue and is full of blood vessels, lets the medicine go straight into the bloodstream when the tablet breaks. It is very important to follow the directions for each sublingual drug exactly to make sure it works right.
The fact that Tesamorelin comes in sublingual tablet form makes it very easy to use and has helped it become very popular. Because it’s easy to use and can be customized, users can quickly find and change their ideal dosage. Also, each tablet contains 1 mg of Tesamorelin, and there are 30 tablets in a package, for a total of 30 mg. This makes dosing easy and accurate.
Importantly, the product’s dependability is boosted by the fact that it is very pure—an impressive 99% purity was confirmed by both first- and third-party laboratories. With this guarantee of purity, Tesamorelin in tablet form looks better and is more trustworthy.
How does Tesamorelin Work?
Image source: Pubchem
Tesamorelin imitates the natural hormone GHRH, a growth hormone secretagogues that usually prompts the release of growth hormone from the pituitary gland in the brain. This growth hormone has diverse effects, such as promoting growth thus addressing growth hormone deficiency and growth rate, regulating metabolism, and influencing body fat distribution. [R]
Growth hormone in turn affects how fats are metabolized. It promotes the breakdown of fat reserves and prevents the buildup of fat, particularly around the abdomen. [R]
Tesamorelin biochemically increases the activity of beta-fatty acid oxidation. This process involves the breakdown of fatty acids, releasing energy that can be utilized by the body, especially during periods of fasting. By upregulating beta-fatty acid oxidation, Tesamorelin promotes the efficient utilization of stored fats as an energy source hence the breakdown of fats. [R]
1. Managing Fat Accumulation in HIV Patients
HIV-1 infection triggers inflammation in fat tissue, causing lipodystrophy and related metabolic problems. [R] Lipodystrophy is a condition where fat is unevenly distributed in the body, leading to loss in some areas and gain in others. In HIV patients on antiretroviral therapy, it often affects the face, arms, legs, buttocks, and trunk.
Research was done to assess Tesamorelin’s effectiveness and safety in treating lipodystrophy related to HIV. The findings showed that Tesamorelin effectively improves body fat distribution and body image in HIV patients with lipodystrophy over 26-52 weeks. This makes Tesamorelin a valuable treatment option for managing HIV-associated lipodystrophy. [R] [R]
2. Improves Liver Performance
In people with HIV and belly fat, Tesamorelin helps reduce the fat inside the belly. A study looked at whether this fat reduction is connected to changes in liver enzymes. The research involved 806 HIV patients. Those who had a significant reduction in belly fat (called “responders”) also experienced better liver enzyme levels compared to those who didn’t have much fat reduction. This improvement in liver enzymes continued even after 52 weeks, even if the patients were given a fake treatment instead of Tesamorelin. Tesamorelin not only reduces belly fat in HIV patients but also improves liver enzyme levels, which is beneficial for their overall health. [R]
3. Enhancing Heart Health
In a study with over 19,000 people living with HIV (PLWH) and a similar number without HIV, researchers examined different heart-related problems like atrial fibrillation, peripheral artery disease, stroke, and any cardiovascular disease (CVD)-related hospitalization. The results revealed that PLWHs are more likely to face an increased risk of cardiovascular diseases, particularly heart failure and stroke. As the HIV population gets older, it’s important to develop strategies to promote heart health and prevent cardiovascular diseases in this group. [R]
4. Promote Fat Loss
Even though Tesamorelin has a well-known reputation for helping people lose fat, this article wants to show you some facts that prove it for sure. If you’ve been having trouble losing fat, these results are a strong indication that Tesamorelin does work. Check out the benefits of Tesamorelin that have been backed by science and show promise for people who want to lose fat and see results.
In one study, researchers investigated the use of tesamorelin to reduce the accumulation of visceral adipose tissue (fat around internal organs) in patients with HIV undergoing antiretroviral therapy. The trial included 412 HIV-infected patients, predominantly men, with abdominal fat accumulation. Participants were randomly assigned to receive daily subcutaneous injections (shots given under the skin) of either 2 mg of tesamorelin or a placebo for 26 weeks. In conclusion, daily tesamorelin for 26 weeks effectively reduced visceral fat and improved lipid profiles in HIV-infected patients experiencing central fat accumulation due to antiretroviral therapy. [R]
Obesity involves having an excess of fat, both under the skin in the abdominal area (SAT) and around internal organs in the abdominal cavity (VAT). The accumulation of fat in these regions is a key factor in the health implications associated with obesity. In obese subjects, tesamorelin has also shown promising results. In a careful and unbiased study where neither the participants nor the researchers knew who got the real treatment and who got a fake one, tesamorelin was found to be effective in reducing a specific type of belly fat called visceral adipose tissue (VAT). When compared to a fake treatment (placebo), tesamorelin also showed positive changes in other aspects of body composition like lean body mass, total fat, and waist circumference. Importantly, there were no significant negative effects observed during the study. In animal testing with rats, there were no noticeable differences in side effects between the group that received tesamorelin and the one that got the fake treatment. [R]
In another situation conducted in the USA, researchers investigated the effects of tesamorelin on liver fat and histology in people with HIV and non-alcoholic fatty liver disease (NAFLD), a common condition in this population. The study involved 61 patients with HIV and a hepatic fat fraction of 5% or more. Participants were randomly assigned to receive either tesamorelin 2 mg daily or a placebo for 12 months, followed by an additional 6-month phase where all participants received tesamorelin. The primary goal was to measure the change in hepatic fat fraction after 12 months. Results showed that patients receiving tesamorelin had a greater reduction in hepatic fat fraction compared to those receiving placebo. After 12 months, a significantly higher percentage of individuals in the tesamorelin group achieved a hepatic fat fraction of less than 5% compared to the placebo group. [R]
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5. Promote Cognitive Enhancement
Beyond its well-established role in aiding fat loss, Tesamorelin emerges as a potential game-changer in addressing cognitive challenges. In a recent study published in the Archives of Neurology, researchers investigated the effects of tesamorelin, a long-acting analog of somatoliberin (growth hormone-releasing hormone), on cognition in individuals with mild cognitive impairment and healthy older adults. The study involved 152 adults aged 55–87 years, with 137 completing the study. Participants self-administered 1 mg of tesamorelin daily for 20 weeks. The results showed that tesamorelin had positive effects on executive function and, to a lesser extent, short-term verbal memory. Cognitive function improved in healthy adults, and the expected decline in those with mild cognitive impairment was lessened. The study suggests that treatment with growth hormone-releasing factors, like tesamorelin, can benefit specific cognitive abilities affected by normal aging and the early stages of Alzheimer’s disease. [R]
6. Memory Preservation
In a research study with 124 participants aged 55-87, both men and women, they were given tesamorelin or a placebo through injections for 20 weeks. The participants included both healthy older adults and those with mild cognitive impairment (MCI).
The findings indicated that tesamorelin had positive effects on brain function for both groups. It improved executive function, which involves skills like decision-making and shifting attention, in both healthy older adults and those with MCI. There were also positive trends in working memory, the ability to hold and manipulate information temporarily. Notably, tesamorelin significantly enhanced delayed verbal recall, particularly for adults with MCI, who are at a higher risk of developing Alzheimer’s disease.
The study suggests that short-term use of tesamorelin can be beneficial for cognitive functions, especially executive function and verbal memory, in both healthy and memory-impaired older adults. [R]
There are other benefits for tesamorelin. A few of the label claims have been reported by users:
7. Improved Muscle Mass
An individual mentioned that in studies of HIV patients with higher abdominal fat tesamorelin was effective, it also added some skeletal muscle mass. [R]
True enough, an exploratory analysis aimed to investigate the effects of tesamorelin on muscle density and area, in clinical trials conducted in the U.S. and Canada. Compared to a placebo, tesamorelin led to significant increases in the density of various trunk muscle groups, including the anterolateral/abdominal and rectus muscles. Additionally, there were notable increases in the total area of the rectus and psoas muscles, as well as in the lean muscle area of all four trunk muscle groups. The findings suggest that tesamorelin effectively increased both the area and density of skeletal muscles in these individuals. [R]
8. Potential Stacking with other Drugs
“Stacking” often refers to the practice of combining different supplements or drugs to enhance their overall effects. [R] One user combined Tesamorelin and AOD9604 and saw fantastic results in the stomach area within 60 days. The user noticed a significant improvement in hunger levels too, although I continued to eat a healthy diet with a focus on protein and nutritious foods. [R]
When using an injection-type form for medication, one may experience redness, itching, pain, irritation, or bruising at the injection site, along with possible muscle aches. These effects are generally mild. In some cases, this medication may increase blood sugar levels, potentially causing or worsening diabetes. [R]
In rare circumstances, severe side effects may include anxiety, dizziness, headaches, increased Inflammation, and irregular heartbeat. [R]
Is Tesamorelin Legel?
Tesamorelin is a prescription drug sold under the brand name EGRIFTA SV. Regulators in several nations, including the US, have licensed it to treat excess abdominal fat in individuals with lipodystrophy who are HIV-positive.
Tesamorelin can only be legally obtained with a prescription from a qualified healthcare provider. Medication approval and legal status are subject to change. [R]
In existing market forms, it usually comes in vials containing 2 milligrams of the drug and is given daily as a subcutaneous injection into the abdomen. It’s important to change injection sites in the abdomen regularly to prevent irritation and skin damage. [R]
Furthermore, it has been found out that as per results or intention of usage. Distinct doses from 2, 1.4, or 1 mg can be prescribed. Also, there are diluent doses of 0.35 and 0.5mL. [R] Therefore it’s important to confirm the most recent details with a healthcare professional or the appropriate authorities.
Is Tesamorelin FDA Approved?
Tesamorelin has been given FDA approval to treat lipodystrophy in HIV-positive patients.
What is the Difference between the Sermorelin Treatment and Tesamorelin?
The major difference between sermorelin therapy and Tesamorelin lies in their clinical uses. Sermorelin is primarily employed to stimulate growth hormone production, often for growth hormone deficiency and anti-aging purposes. On the other hand, Tesamorelin is specifically indicated for reducing excess abdominal fat in HIV-infected patients with lipodystrophy. The choice between the two depends on the medical condition being treated and the desired outcomes.
How Long Does it Take to See Results?
The effect of Tesamorelin will depend on how your body reacts to the medication. Several factors, such as the patient’s physical condition, the dosage, and the duration of treatment, might affect how long it takes to see results. Nonetheless, following 26 weeks of treatment in a clinical trial, patients using Tesamorelin for weight loss experienced a considerable reduction in visceral fat. It is essential to note that long-term administration and higher doses may pose potential risks. Additionally, existing conditions could lead to drug interactions, altering normal physiology. Therefore, further studies are necessary to obtain comprehensive results and ensure the safe and effective use of Tesamorelin in regulating growth hormone secretion.
Where to Buy Tesamorelin Online?
Purerawz has been one of the market’s hidden heroes since 2014, constantly releasing high-quality products that contribute to people’s overall health and happiness. They’ve been working with Sermorelin Peptide for a long time, so they’re a safe bet. Are you still unsure? Customer testimonials can be found on the Purerawz website.
This trustworthy online shop is the best place to buy anything. They have a round-the-clock chat service and cite research to back up their claims. If you haven’t tried them yet, do so immediately. Obtain the top-tier Tesamorelin immediately!
Puerawz Tesamorelin can be the solution you’ve been looking for if you’re sick of attempting to gain weight and lose fat that just won’t go away. The team created Tesamorelin, a synthetic growth hormone-releasing hormone (GHRH) analog, which stands out as a versatile therapeutic option with a wide range of potential benefits. From addressing the challenges of lipodystrophy in HIV patients to promoting cognitive enhancement, Tesamorelin has demonstrated significant efficacy. The introduction of a sublingual tablet formulation has added to its appeal, providing a convenient and efficient means of administration.
Tesamorelin emerges as a promising therapeutic option with multifaceted benefits, contributing to improved body composition, cognitive function, and overall well-being, especially in specific patient populations. However, its usage should be approached under the guidance of healthcare professionals, considering individual health conditions and needs.