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Laxogenin (2024 Guide): Results, Effects, Dosage & More

Laxogenin (Guide): Results, Effects, Dosage & More

Laxogenin, otherwise known by its research name, 5 alpha hydroxy laxogenin, is one of the hottest supplements on the market right now.

A natural extract from a seemingly innocuous plant, this powerful compound has the power to put your muscle growth into overdrive.

In fact, some people have even compared laxogenin to Anavar, an anabolic steroid—but is it really that powerful, or is that just a bro-science myth?

Today, we’ll offer an evidence-based approach to this supplement, and cover the best dosage, the benefits, what the research says, and more.

What is Laxogenin?

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Laxogenin, or more formally known as 5a-hydroxy-laxogenin, is a highly anabolic compound that encourages lean muscle mass growth in the body.

Laxogenin is extracted from the roots of the coveted Smilaz Sieboldii plant, which is a vine-like plant that’s native to East Asia, and the Americas. [R]

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While it’s often sold alongside other research chemicals such as SARMs, laxogenin is actually not a SARM, nor is it hormonal, or a pro hormone.

This makes laxogenin a favorite amongst modern bodybuilders, due to it not requiring a PCT, yet still being a very effective muscle building agent.

Overview of Laxogenin

Before we get into the laxogenin studies, health benefits, top products to stack this supplement with, and other details, we’d like to offer an overview first of the positives and negatives of taking this compound.

Benefits of this Supplement:

  • Great For Building Muscle
  • Rapidly Shred Fat
  • Doesn’t Lower Testosterone Levels
  • Stronger Than Most Supplements
  • All Natural (Not Synthetic)
  • Enhanced Athletic Performance
  • Faster Recovery
  • Increased Protein Synthesis

Side Effects of this Supplement:

  • More Studies Needed
  • Can Cause Headaches
  • Can Cause Nausea

Overall, laxogenin is a phenomenal supplement that will enhance protein synthesis, encourage body recomposition, and much, much more.

Legality & Where to Buy

If you’re just skimming and wondering if laxogenin is legal to buy, then thankfully you’re in luck. Laxogenin is 100% legal to buy and sell online.

While laxogenin isn’t approved by the FDA for human consumption (yet), it’s still safer than many supplements out there, and is extremely powerful. When you consider the fact that laxogenin is a natural steroid with very few side effects, it’s no wonder that people buy it online and use it in droves.

Our recommended source for laxogenin is Pure Rawz—no filler, fake ingredients, or synthetic BS. Just pure, unadulterated products. In fact, their recent 3rd party verification lab tests show that their laxogenin is 99.9% pure, which is about the purest laxogenin you’ll be able to find online.

Each of their supplements is verified by a 3rd party lab for purity, so you can rest assured that the products you purchase are at least 99.9% pure—because believe us, nobody wants impure laxogenin.

How Does Laxogenin Work?


Once ingested, laxogenin quickly begins exerting anabolic effects on the body, specifically by binding onto cells and activating the AKT1 protein. [R] This is one of the things that makes laxogenin unique—rather than increasing testosterone, or messing with your body’s natural hormone production, it simply signals your body to build more muscle.

After the laxogenin binds to the ATK1 protein receptors, your body will immediately begin building muscle by increasing protein synthesis, which explains the anabolic, Anavar-like effects of laxogenin. Increases in protein synthesis, particularly in muscle cells, are directly linked to an increase in muscle mass. [R]

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In addition to this, taking laxogenin as a supplement also increases cAMP levels, similar to the ECA stack, which leads to an accelerated rate of fat loss in the body.

To put it bluntly, laxogenin is one of the best natural supplements these days for both building muscle and shredding fat—that’s a fact. [R]

Laxogenin Health Benefits

laxogenin plant

Most users report gaining 15-20 pounds of lean muscle mass from a single 2-3 month cycle of this supplement—but the benefits don’t stop there.

Laxogenin has a wide variety of benefits, and while more research must be done on the potential long term side effects of this natural plant extract, most preliminary research suggests that it’s safe to take.

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Benefits of Taking This Supplement:

  • Rapid Muscle Growth
  • Enhanced Recovery Speed
  • Accelerated Fat Loss
  • Decreases Cortisol Levels
  • Increases Protein Synthesis

Most users report that the biggest benefit of taking laxogenin is for doing a lean bulk. This compound is great for bulking up and still staying lean.

Rapid Muscle Growth

One of the biggest reasons that people take laxogenin is to increase their lean muscle mass, while also to lose fat at the same time. In fact, many studies have confirmed the muscle-building, anabolic properties of laxogenin. [R]

Laxogenin could technically be classified as a “natural steroid,” and is similar to another plant chemical known as brassinosteroids, or phytoecdysteroids, which have been shown to rapidly increase the rate of muscle growth in both animals and humans. [R] [R]

In fact, it isn’t uncommon for many users to report gaining upwards of 10 pounds of muscle from a single cycle of laxogenin, and this is from a natural steroid that has very little side effects, so gaining 10 pounds of lean muscle (or more) in just a matter of 4-8 weeks is quite impressive.

Accelerated Fat Loss

Similar to SARMs such as Cardarine and Andarine, laxogenin exerts a powerful fat loss effect on the human body. While no studies have been directly conducted on these exact effects of laxogenin, we can determine that this effect exists due to the existing research on its anabolic factor, as well as anecdotal evidence.

When it comes to fat loss, one thing that will greatly aid this is an increase in muscle mass. Why? Because having muscles means that your body has to burn more calories to build them and upkeep them—so by simply taking laxogenin and using it to build muscle, you’ll end up losing fat in the process.

In addition to this, there is ample anecdotal evidence from forums, Reddit, and other websites, where users post their laxogenin results. As you can see in the section below where we cover this, it’s not uncommon for people to lose upwards of 10 pounds of fat (while also gaining muscle) from a single laxogenin cycle.

Laxogenin Results

Laxogenin Results

Now, does laxogenin really work? Well, take a look at the laxogenin before and after pictures taken above—that should answer your question, no?

In all seriousness, most users who take laxogenin experience rapid muscle gain and fat loss, often completely transforming their bodies in the process.

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On average, most users can expect to gain 10-15 pounds of muscle from a single cycle of laxogenin, and potentially even more with great diet.

In fact, there’s reports of people gaining up to 20 pounds from using this natural plant steroid, and although this isn’t common, it’s certainly possible if you have a great workout routine and near-perfect diet.

Dosage & Safety Guidelines

shredded bodybuilder

While there’s really no FDA approved dosage for humans, if we look at the anecdotal cycle logs and user reports, we can get an idea of what to aim for.

In general, dosages for laxogenin range anywhere from 25 mg if you’re a beginner, all the way up to 200 mg per day, or even more in some cases.

  • Beginner: 25 mg per day
  • Intermediate: 50 mg per day
  • Advanced: 100 mg per day

If you look around online, you’ll see people talking about dosages as high as 200 milligrams per day, but they’re likely not getting real, pure laxogenin.

With 99% pure laxogenin, like from Pure Rawz (which we recommend), you don’t need to take 200mg—even just taking 25mg/day will do a lot.

Bodybuilding Stacks

Laxogenin, being a natural plant steroid, works very well with SARMs for both bulking and cutting, as well as doing a full on recomposition cycle.

Bulking StackCutting Stack
Laxogenin – 50mg/dayLaxogenin – 50mg/day
MK 677 – 25mg/dayRAD 140 – 15mg/day
Ligandrol – 20mg/dayCardarine – 10mg/day

Laxogenin mainly shines in its ability to build lean muscle mass, which makes it an exceptional compound for doing a lean bulking cycle.

It pairs very well with bulking SARMs like MK 677 and Ligandrol, but can also pair well with cutting SARMs like Andarine and Cardarine.

Laxogenin Side Effects

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Now, of course, you’re probably wondering if laxogenin has any side effects. After all, how can a supplement be so strong, without having any sides?

Thankfully, due to the non-hormonal nature of laxogenin, most users experience little to no side effects unless taking huge dosages each day.

Potential Side Effects:

  1. Upset Stomach
  2. Headaches
  3. Diarrhea

The most common side effect of this supplement is simply having a headache, and most users report that this only happens in the upper dosage range (200mg or more per day).

Fortunately, the majority of users who try this supplement do not report any severe or long-lasting side effects—although more research should certainly be done on the long term side effects of this drug.

The Bottom Line

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In summary, most of the clinical research suggests that laxogenin is very safe to take in dosages as high as 200mg per day, although most people don’t need that much.

If you do decide to try laxogenin, be sure to get it from a high quality research chemicals vendor that has intensive 3rd party testing for purity.

Personally, we recommend you buy laxogenin from Pure Rawz—they’re one of our favorite online vendors, and best of all, if you use the code “MD15” you’ll get 15% off your order.

If you believe we missed anything out, feel free to shoot us a comment down below, and we’ll do our best to respond to you in a timely manner!


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