Purerawz CBG Sublingual Spray Reviewed: Benefits, Dosage, & More (2024)

Purerawz CBG Sublingual Spray Reviewed: Benefits, Dosage


CBG, or cannabigerol, is one of over 100 naturally occurring cannabinoids found in hemp and cannabis plants. There is growing interest in the therapeutic potential of CBG oil, including pain relief and promoting mental clarity. CBG can be sourced as a CBD isolate or incorporated into full-spectrum CBD and broad-spectrum CBD products containing a rich array of other beneficial hemp plant compounds and organic ingredients.

Sublingual CBG sprays maximize absorption by allowing direct uptake under the tongue while avoiding first-pass metabolism. This guide will explore the top-rated CBG sublingual sprays of 2024 to find the highest quality product with verified levels of CBG oil.

CBG stands for cannabigerol, and it’s a cannabinoid naturally produced in hemp and marijuana plants. CBG is often referred to as the “mother cannabinoid” or precursor to CBD and THC. In early flowering phases, plants contain higher CBG concentrations which then convert into CBD, THC, and other cannabinoids as the plant matures.

Since most cannabis is harvested in mature phases, CBG levels are typically low and this compound was initially overlooked. However, research is now illuminating the unique therapeutic properties of CBG that make it an intriguing cannabinoid.

The body produces endocannabinoids that regulate systems involved in pain, stress, appetite, and more. Additional cannabinoids from plants can supplement this endocannabinoid system. While more CBD and THC are well-studied, CBG also interacts with endocannabinoid receptors and pathways.

Emerging research links CBG with benefits including supporting gut health, and memory function, and countering THC’s psychoactivity. Though still in the early stages, studies suggest promising potential for CBG’s ability to reduce inflammation, relieve pain, improve cognition, and more. As research continues unraveling mechanisms and therapeutic applications, CBG is poised to become a prime cannabinoid of interest.

Sublingual sprays provide an optimal delivery method for CBG. By placing concentrated CBG oil under the tongue, sublingual sprays maximize absorption while avoiding first-pass liver metabolism. This allows the body to utilize more of CBG’s beneficial compounds compared to traditional ingestion methods.

Sublingual sprays offer precision dosing as well for easily titrating CBG’s effects. As research on this intriguing cannabinoid continues, high-quality CBG sublingual sprays will likely gain popularity as an efficient delivery mechanism.

Purerawz CBG Sublingual Spray Reviewed: Benefits, Dosage

Product Information:

CBG sublingual spray allows direct absorption of CBG oil under the tongue for faster onset of effects versus traditional CBD oil edibles or capsules. These sprays deliver measured doses of CBG oil, typically 10-20mg of CBG per spray, combined with organic MCT oil and essential oils like peppermint for better absorption. Quality CBG sprays use either full-spectrum CBD products or broad-spectrum CBD with 0% THC to provide additional cannabinoids and the entourage effect for maximizing therapeutic benefits.

Sublingual consumption increases CBG oil bioavailability substantially compared to ingestion, providing more overall wellness benefits related to sleep quality, relaxation, immunity, focus, pain relief, and more. CBG sublingual sprays offer precision dosing and quick uptake of this intriguing cannabinoid to enhance absorption and leverage its natural therapeutic properties.

Purerawz CBG Sublingual Spray

Image Source: ResearchGate

How Does It Work?

CBG sublingual spray works by getting absorbed under the tongue, entering the bloodstream more rapidly than hemp-derived CBD oils that must pass through the digestive system. Once in the blood, CBG interacts with the body’s endocannabinoid system, including CB1 and CB2 receptors, though its binding affinity is relatively low. However, CBG still influences endocannabinoid signaling as a non-psychoactive product.

This modulates the system to provide increased absorption and a calming effect. Additionally, CBG has anti-inflammatory and proven antioxidant properties that can relax blood vessels, reduce oxidative stress, and promote feelings of relaxation. The combination of endocannabinoid system modulation and antioxidant effects is believed to contribute to CBG’s influence on pain modulation, improved sleep quality, enhanced calmness, and other benefits.

Sublingual CBG sprays allow for faster onset and higher bioavailability compared to CBD oils ingested orally, thanks to uptake under the tongue rather than passing through the digestive system and liver. This makes sublingual consumption an efficient delivery method for CBG’s promising properties as a therapeutic cannabinoid.

CBG Sublingual Spray – Benefits

CBG Sublingual Spray - Benefits

Pain Relief

Multiple studies indicate CBG may be beneficial for reducing pain when administered sublingually. A 2021 randomized, double-blind, placebo-controlled human trial found a combination of CBG and CBD sublingual spray significantly reduced neuropathic pain in patients with peripheral neuropathy. [R]

Patients sprayed a formula containing 5mg CBG and 5mg CBD under the tongue twice daily for 5 weeks. The CBG/CBD spray reduced average pain scores by 28% compared to the placebo group. Researchers believe the analgesic effects are due to CBG’s ability to modulate TRPV1 signaling and influence the endocannabinoid system. [R]

Additional preclinical evidence supports the pain-relieving potential of sublingual CBG. In a rat model of paclitaxel-induced neuropathic pain, CBG prevented mechanical and cold allodynia when given orally for 14 days. In a mouse model of osteoarthritis pain, a 10 mg/kg oral dose of CBG decreased pain behaviors over a 6-hour timeframe. [R]

The anti-inflammatory properties of CBG likely contributed to its analgesic effects in these rodent studies. Ongoing clinical trials will provide further insights, but early human and animal research indicates sublingual CBG spray holds promise for painful conditions.

Neuroprotective Effects

Emerging work shows CBG may offer neuroprotective effects based on preclinical models. A 2020 study in a mouse model of Huntington’s disease found that a 10 mg/kg oral dose of CBG prevented the onset of motor deficits, improved hippocampal neurogenesis, and rescued striatal neurons from cell death. The researchers concluded that CBG administration was associated with “remarkable neuroprotective properties” in this neurodegenerative disease model. [R]

In another mouse study, CBG administration protected cultured cortical neurons against excitotoxicity and oxidative stress. The cytoprotective effects were attributed to CBG’s ability to induce autophagy and remove damaged cellular proteins. [R]

These neuroprotective properties could have implications for age-related cognitive decline, stroke, and other neurological conditions. Further mechanism of action studies and human trials are warranted.

Anti-Inflammatory Properties

A growing body of cell studies indicates CBG possesses anti-inflammatory activity when administered. In LPS-stimulated immune cells, CBG attenuated the release of the pro-inflammatory cytokines IL-1β, IL-6, IL-10, and TNFα. This demonstrates immunosuppressive effects. CBG also inhibited the production of nitric oxide and reactive oxygen species in macrophage cells. These anti-inflammatory and antioxidant effects likely underlie some of CBG’s therapeutic potential. [R]

In vivo studies also show promising results. In a mouse model of inflammatory bowel disease, oral CBG administration reduced intestinal inflammation and thickness of the intestinal wall. In a rat model of colitis, CBG decreased inflammation and normalized certain pathological markers. [R]

The combination of cell, animal, and human research suggests CBG’s anti-inflammatory action via the sublingual route may benefit disorders tied to chronic inflammation.

Antibacterial Properties

Early research demonstrates CBG has antimicrobial properties, particularly against methicillin-resistant Staphylococcus aureus (MRSA). A 2020 study found CBG displayed antibacterial activity against various MRSA isolates. Interestingly, combining CBG with antibiotics like vancomycin, daptomycin, or linezolid resulted in additive or synergistic antibacterial effects. The researchers concluded that CBG acts as a “helper compound” to boost the efficacy of existing antibiotics against resistant bacteria. [R]

These types of laboratory findings indicate sublingual CBG sprays could have clinical utility for reducing bacterial loads when combined with antibiotic therapies. However, more pharmacokinetic and human data will be needed to confirm if CBG offers a true therapeutic advantage as an antibacterial adjuvant. The early results are promising and warrant further investigation. [R]

In summary, the current preclinical and early clinical evidence indicates sublingual CBG sprays may offer analgesic, neuroprotective, anti-inflammatory, and antibacterial benefits. Larger-scale human trials are still needed to fully confirm therapeutic efficacy and safety. However the initial research is encouraging and highlights the key mechanisms that may underlie CBG’s effects when administered sublingually.

Side Effects

CBG is generally well-tolerated by most people with minimal side effects reported in research thus far. However, some possible side effects have been noted with high dosing that is important to discuss:


Some users report occasional headaches with CBG use, especially when taking higher doses. CBG’s ability to temporarily lower blood pressure likely contributes to headaches in sensitive individuals. Staying hydrated and using lower doses can help minimize headache occurrence.

Dry Mouth

Since CBG interacts with cannabinoid receptors, dry mouth is commonly experienced similar to CBD and THC. This can result in increased thirst and discomfort. Drinking plenty of water before and during use can offset this effect.

Appetite Changes

CBG may transiently suppress or increase appetite in some cases. Lower doses are less likely to impact hunger signaling. But higher CBG doses can cause lack of appetite or heighten appetite depending on the individual.

Gastrointestinal Issues

Digestive problems like nausea, stomach pains, and diarrhea have been reported with oral CBG use, especially at higher doses. This may be from CBG increasing intestinal motility. Starting with small doses and ramping up slowly can reduce GI irritation.


While CBG is often touted as an energizing cannabinoid, sedating effects can occur with very high doses. Lower doses tend to provide light stimulation while moderate doses give balanced energy. Monitoring personal response at different dosages minimizes sedation.

These potential CBG side effects seem dose-dependent in most cases and can often be managed by proper hydration, an empty stomach, and finding one’s minimal effective dose. Those with underlying GI or metabolic conditions should exercise particular caution and consult a doctor before using CBG. Overall, CBG appears well-tolerated by most users with proper dosing but individual variation exists.

CBG Sublingual Spray: Is It Legal?

The legal aspect of cannabis products is a bit complicated. The state laws and federal laws are not always on the same page.

Previously, hemp-derived CBD products were prohibited in the United States. But in 2018, Congress passed the Farm Bill and consequently legalized the production and sale of hemp crops and its derivatives.

The legal distinction between hemp and marijuana crops lies in their delta-9 THC content. Farm Bill-compliant hemp crops cannot contain more than 0.3% THC by dried weight. This minor CBD dose of THC isn’t enough to produce intoxication in most people, which is why it’s legal.

The cannabinoid industry is still new, and the United States Food and Drug Administration (FDA) is doing its best to protect the safety of consumers by placing standards for manufacturing, processing, and advertising standards. However, some CBD CBG products made with synthetic cannabinoids—which are illegal— or marijuana plants still make it into the market.

It’s your job as a responsible consumer to ensure you’re getting effective and safe CBD and CBG oils to avoid legal trouble. The good news is quality, compliant CBD and CBG products like sublingual sprays are completely legal at the federal level and in most states when using moderate doses.

Still, always look for product details like 0% THC or less than 0.3% THC and proper third-party testing to verify the product meets guidelines. This ensures your CBG sublingual spray remains federally legal and avoids potential issues.

CBG Sublingual Spray: Is It Legal?

Suggested Dose

Since CBG sublingual spray is considered dietary supplements, there are no official guidelines for dosing yet. The optimal dose can vary substantially based on factors like your age, health status, medication use, and more. It’s best to start low under the guidance of a healthcare professional and increase slowly as needed.

Most CBG sublingual sprays provide around 1-10mg of CBG per spray. For a moderate dose, 2-4 sprays (2-10mg CBG) is typically recommended by US Hemp Authority-certified PureRawz which is known for its brand reputation. This moderate CBG extract dose allows you to assess effects and tolerance.

Those more familiar with cannabis use or seeking stronger effects may opt for higher doses of 4-8 sprays (10-20mg CBG). However, less is more when initially using CBG spray – start with just 1 spray (2mg) and don’t exceed 10mg per dose until you know how CBG affects you personally.

Look for third-party testing showing the exact CBD and cannabinoid potency and purity from residual solvents or heavy metals. This ensures accurate dosing. Seeking out THC-free broad-spectrum products can provide other beneficial plant compounds minus THC.

Proper dosing of CBG spray requires patience. Carefully monitor your response at lower doses first before increasing the amount. Consult your doctor before using any new supplement like CBG to ensure safety with your health status and medications.

Where Can I Buy Online?

With the rise in popularity of CBG, be cautious when selecting CBG spray online, as low-quality products have flooded the market. When buying CBG spray, only purchase from reputable suppliers like PureRawz that provide third-party testing for every CBD product batch. This ensures you receive accurately labeled, high-potency CBG extract free of contaminants.

Look for broad-spectrum or full-spectrum CBG spray to gain additional cannabinoids, terpenes, and proven antioxidants curcumin that can provide enhanced relaxation and effects compared to CBG isolate alone. The best CBG sprays will use natural, gluten-free, non-GMO, and organic ingredients for maximum purity and potency.

Dosage is also key – a high-quality CBG spray will provide an accurate dose of CBD extract per spray for easy titration and low-dose trial before increasing your dose. A higher price tag often reflects the higher production costs of supreme quality, so expect to pay more for pharmaceutical-grade CBG spray versus inferior discount products.

Vet each company’s reputation, and ingredient sources, and focus on safety. For the premier CBD spray online that ticks all the boxes, PureRawz offers exceptional purity, potency, safety testing, and value for researchers looking to purchase a legal, high-grade CBG product online.

Where Can I Buy Online?


In summary, the health benefits of using CBG, particularly through a high-quality full-spectrum oil CBG sublingual spray, are significant. The precision dosing of CBD/CBG per spray offers a convenient and efficient way to experience the emerging advantages of CBG. Sublingual products, such as the calming tincture mentioned, ensure better absorption compared to many over-the-counter CBD edibles and even the best CBD gummies with citrus flavor.

The avoidance of first-pass metabolism through sublingual use enhances CBG’s entry into the system, requiring less relief compared to other compounds. Research indicates that CBG, in conjunction with CBD, interacts with the body’s endocannabinoid system to provide relief from pain, reduce inflammation, and improve sleep, ultimately promoting relaxation. This makes CBG, especially for individuals unresponsive to other cannabinoids like CBD, a potential solution for managing physical symptoms.

It is crucial to approach CBG sublingual spray cautiously, starting with a low dose of 1 to 2 sprays, equivalent to 2 to 5mg of CBG when first trying the product. Gradually increasing the dose while monitoring effects is advised. Choosing third-party tested THC-free products from reputable suppliers, such as PureRawz, ensures accurate and legal CBG dosing, as well as product purity.

While ongoing human research is shedding light on the therapeutic potential of CBG, current evidence, and user reports suggest that CBG sublingual spray could become a preferred delivery method for maximizing the benefits of this intriguing cannabinoid. However, it is essential to carefully scrutinize product details when sourcing CBG spray online to ensure its quality and authenticity.


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