Liposomal Melatonin: Here’s Everything You Need To Know

Counting sheep won’t help you fall asleep if you have insomnia. Neither will taking a warm shower or reading a book before bedtime. The only thing that could help you doze off is melatonin – an internal hormone your brain secretes in response to darkness.

Melatonin puts us to sleep by regulating our circadian rhythms, our body’s internal clock that controls our sleep patterns, and by slowing down our physiological functions. Elevated levels of melatonin in the body make us feel drowsy and, before we know it, nudge us towards sleep.

Unfortunately, this step-by-step pattern only applies to those of us who don’t have insomnia. Others, whose body isn’t producing adequate amounts of melatonin, must take a nutritional supplement containing melatonin to fall asleep. Liposomal Melatonin is one such supplement.

What is Liposomal Melatonin?

Liposomal Melatonin is a dietary supplement that helps you fall and stay asleep. Liposomal supplements provide the body with a delivery system that assures rapid uptake and quick delivery into the cells – which means you won’t have to wait for long to feel their effects.

Other supplements that you usually take must be broken down by your digestive system before your tissues can absorb them. That isn’t the case with liposomal supplements. They bypass first-pass metabolism and breakdown in the liver, ensuring direct absorption by the cells.

That is superb news because it means you won’t have to wait for long to feel the effects of liposomal melatonin. You’d be able to enjoy sleep much quicker than if you had taken other sleep-aid supplements, almost all of which take the regular route of your digestive system.

What’s more, liposomal melatonin can also benefit those of you who are highly sensitive to melatonin. Its liquid format – liposomal melatonin doesn’t come in capsule form – allows its manufacturer to ensure that each dose contains too little melatonin to induce a reaction from your body.

Best Liposomal Melatonin ?

The best place to buy 99.9% pure liposomal melatonin is from Gorilla Mind. They have the highest quality liposomal melatonin on the market, for the most competitive prices, and it’s also very well dosed and will last you a VERY long time if you use it according to the dosage guidelines.

Make sure you have your doctor on board before you start taking these supplements. Follow the advice given on their label for daily dosage. Start with a low dose (1pump or tea/tablespoon per day) and take it up from there per your needs.

Can You Take It Every Night?

You can take liposomal melatonin every night, but only for the short term. That isn’t because taking this supplement daily for the long-term might expose you to any side effects. It’s only because there isn’t much information available about its long-term safety.

However, if you want to be on the safe side, you might want to consult with your healthcare provider. That is especially true if you’re thinking of giving melatonin to children, which should only be done after you have consulted your pediatrician.

Liposomal Melatonin vs. Regular Melatonin

This question is important because if melatonin is solely responsible for putting us to sleep, why can’t we take any other supplement containing this hormone. Why are we asking you to prefer liposomal melatonin over all the other melatonin supplements available on the market?

Research tells us that when you take your typical oral supplement containing melatonin, your cells absorb only 15% of the melatonin. The rest of it goes to waste. In contrast, the absorption rate of liposomal supplements is a staggering 85%. Let’s illustrate this point with an example. [R]

Assume for a moment that you’re taking 10g of your average melatonin supplement as well as a liposomal melatonin supplement. In the first case, your cells would absorb only 1.5g of melatonin. With liposomal melatonin, however, the amount of melatonin absorbed would be 8.5g.

Which of the two supplements, then, would help you fall asleep quicker? Of course, the liposomal melatonin supplement. By providing your cells with more quantity of melatonin than what they’d get from non-liposomal supplements, it would help you doze off much quicker.

Liposomal Melatonin Benefits

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One of the most sought-after benefits of liposomal melatonin is that it helps you fall asleep quickly. Other conditions that this supplement can cure include jet lag, pre- and post-surgery anxiety, some sleep disorders in children, and delayed sleep-wake disorder.

Here are the conditions liposomal melatonin could help cure:


According to a 2013 study, people with insomnia were able to fall asleep much quicker with melatonin than those taking a placebo. An interesting aspect about the study was that the participants included both adults and children dealing with insomnia. [R]

The study further established that those participants who took melatonin the previous night had an enhanced total sleep time vis-à-vis those taking a placebo. Their overall sleep quality also increased, and they continued getting the benefits even with continued melatonin use.

Jet Lag

Jet lag affects the sleep patterns of persons who travel by air across multiple time zones. People with jet lag may experience disturbed sleep, impaired functioning, daytime tiredness, and digestive problems. They might also find it difficult to memorize things and concentrate.

The good news is that liposomal melatonin has been proven to help with jet lag. Multiple studies on hundreds of air travelers found that melatonin is better than a placebo in improving sleep quality and reducing other symptoms of jet lag. [R]

Delayed Sleep-Wake Phase Disorder

People with the delayed sleep-wake phase disorder (DSWPD) encounter trouble falling asleep at the usual times. They also find it difficult to wake up in the morning. Such people experience poor sleep quality between time periods 2 and 6 a.m.

That’s where the bad news ends. A 2016 study was able to establish that people with DSWPD fell asleep much quicker when they were on melatonin supplements. On average, the study found, the participants took about 22 minutes fewer to doze off.

Pre- and Post-Surgery Anxiety

Most people experience anxiety before undergoing surgery. It’s also natural to feel anxious after the surgery. A survey puts the number of people who feel anxious in the build-up to and immediately after the surgery at up to 80%.

A 2015 review poured over 12 studies that looked at 774 people to assess whether melatonin supplements helped reduce their anxiety levels. The review got ‘strong’ evidence that the ingestion of melatonin before surgery led to reduced anxiety.

Liposomal Melatonin Side Effects

Researchers have declared melatonin safe for short-term use. It doesn’t lead to the many side effects – dependency, reduced response after frequent use, hangover effect after each use – that you may experience with other sleep medications.

Here are various side effects of liposomal melatonin:

  • Headaches
  • Drowsiness
  • Nausea
  • Dizziness

Other, less common side effects of melatonin include mild anxiety, mild tremors, abdominal cramps, reduced focus and concentration, temporary feelings of depression. Because taking it can lead to drowsiness, don’t drive within six hours of taking liposomal melatonin.


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Liposomal Melatonin provides you with the best of both worlds. On the one end, it helps you fall asleep quicker, stay asleep for longer periods and enjoy better sleep quality. This supplement can also reduce your anxiety levels and decrease jet lag symptoms if you’re a frequent traveler.

On the other end, liposomal melatonin doesn’t have any severe side effects. That is despite the fact that it takes less long than other melatonin supplements to get absorbed by your cells while also helping your cells absorb more melatonin than them. What more can you ask for!

Nanotech Project Team

Nanotech Project is dedicated to helping readers discover the safest, and most clinically-based way to apply SARMs, nootropics, anabolics, metabolics, and other research chemicals. We specialize in dissecting research on supplements, and other compounds that bodybuilders often use.

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